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N4bp1 Gene Detail
Summary
  • Symbol
    N4bp1
  • Name
    NEDD4 binding protein 1
  • Synonyms
    MGC:7607
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136825
    NCBI Gene: 80750
Location & Maps
more
  • Sequence Map
    Chr8:86841139-86885258 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      44120 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    N4BP1, NEDD4 binding protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    N4BP1, NEDD4 binding protein 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 9683
    neXtProt AC: NX_O75113

  • Chr Location
    16q12.1; chr16:48538726-48610214 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 23703
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: N4BP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    31 phenotype references
  • All Mutations and Alleles
    29
  • Gene trapped
    25
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving N4bp1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031652 Ensembl Gene Model | MGI Sequence Detail 44120 C57BL/6J ±  kb
transcript ENSMUST00000034074 Ensembl | MGI Sequence Detail 6469 Not Applicable  
polypeptide ENSMUSP00000034074 Ensembl | MGI Sequence Detail 893 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    230 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010937 NEDD4-binding protein 1
  • InterPro Domains
    IPR004088 K Homology domain, type 1
    IPR021869 Ribonuclease Zc3h12a-like, NYN domain
Molecular
Reagents
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  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
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MGI:2142573, MGI:2142863
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 31
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173792 Bracken CP, et al., Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Res. 2011 Mar 22;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory