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Igsf9 Gene Detail
Summary
  • Symbol
    Igsf9
  • Name
    immunoglobulin superfamily, member 9
  • Synonyms
    Dasm1, mKIAA1355, NRT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135283
    NCBI Gene: 93842
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:172481788-172498878 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 79.86 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135283
protein coding gene Chr1:172481774-172498878 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016789
protein coding gene Chr1:178351029-178368082 (+)
A/J MGP_AJ_G0016768
protein coding gene Chr1:171060057-171079026 (+)
AKR/J MGP_AKRJ_G0016734
protein coding gene Chr1:176223254-176240309 (+)
BALB/cJ MGP_BALBcJ_G0016729
protein coding gene Chr1:171598165-171615234 (+)
C3H/HeJ MGP_C3HHeJ_G0016553
protein coding gene Chr1:176797201-176814260 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017191
protein coding gene Chr1:184277152-184294238 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014897
protein coding gene Chr1:162752787-162769811 (+)
CAST/EiJ MGP_CASTEiJ_G0016133
protein coding gene Chr1:176165966-176183057 (+)
CBA/J MGP_CBAJ_G0016527
protein coding gene Chr1:190822930-190840096 (+)
DBA/2J MGP_DBA2J_G0016634
protein coding gene Chr1:169985618-170002744 (+)
FVB/NJ MGP_FVBNJ_G0016631
protein coding gene Chr1:168241504-168259549 (+)
LP/J MGP_LPJ_G0016705
protein coding gene Chr1:179435813-179452887 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016658
protein coding gene Chr1:198056818-198073871 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017227
protein coding gene Chr1:176092935-176111033 (+)
PWK/PhJ MGP_PWKPhJ_G0015919
protein coding gene Chr1:169367045-169384213 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015701
protein coding gene Chr1:175050097-175067189 (+)
WSB/EiJ MGP_WSBEiJ_G0016195
protein coding gene Chr1:176244144-176262816 (+)



Homology
more
  • Human Ortholog
    IGSF9, immunoglobulin superfamily member 9
  • Vertebrate Orthologs
    11
  • Human Ortholog
    IGSF9, immunoglobulin superfamily member 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FP18798, IGSF9A, Nrt1
  • Links
    NCBI Gene ID: 57549
    neXtProt AC: NX_Q9P2J2
    UniProt: Q9P2J2

  • Chr Location
    1q23.2; chr1:159927039-159945661 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10815
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IGSF9
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation are viable and fertile but show abnormal miniature inhibitory postsynaptic currents and increased susceptibility to pharmacologically induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037995 Ensembl Gene Model | MGI Sequence Detail 17091 C57BL/6J ±  kb
transcript ENSMUST00000052629 Ensembl | MGI Sequence Detail 4133 Not Applicable  
polypeptide ENSMUSP00000058275 Ensembl | MGI Sequence Detail 1179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 111
    Genomic 1
    cDNA 106
    Primer pair 3
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2135331
References
more
  • Summaries
    All 33
    Developmental Gene Expression 8
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:68343 Doudney K, et al., Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. Genomics. 2001 Mar 1;72(2):180-92
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory