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Acox2
Gene Detail
 Symbol
Name
ID
Acox2
acyl-Coenzyme A oxidase 2, branched chain
MGI:1934852
Feature Type protein coding gene
Genetic Map
Chromosome 14
4.77 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:8225511-8259353 bp, - strand
From VEGA annotation of GRCm38

  33843 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74473  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: acyl-CoA oxidase
Gene Tree: Acox2

Human
homologs
Human Homolog ACOX2, acyl-CoA oxidase 2, branched chain
NCBI Gene ID 8309
neXtProt AC  NX_Q99424
Human Synonyms  BCOX, BRCACOX, BRCOX, THCCox
Human Chr (Location)  3p14.3; chr3:58505136-58537202 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Acox2 interacts with 57 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process fatty acid beta-oxidation, fatty acid metabolic process, ...
Component peroxisome
Function 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity, acyl-CoA dehydrogenase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (68)    Tissues (53)    Images (12)
Theiler Stages: 15, 19, 22, 23, 26, 28
Assay TypeResults
RNA in situ 53
Northern blot 15
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) cDNA(43) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000035513 (Evidence)
Ensembl Gene ModelENSMUSG00000021751 (Evidence)
Entrez Gene93732 (Evidence)
UniGene28700
DFCITC1581172
DoTSDT.537949, DT.94351156
NIA Mouse Gene IndexU035228
EC1.17.99.3
Consensus CDS ProjectCCDS36801.1
International Mouse Knockout Project StatusAcox2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035513 VEGA Gene Model | MGI Sequence Detail 33843 C57BL/6J ±  kb
transcript OTTMUST00000090947 VEGA | MGI Sequence Detail 2907 Not Applicable 
polypeptide OTTMUSP00000050025 VEGA | MGI Sequence Detail 681 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(215 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
InterPro IPR012258 Acyl-CoA oxidase
InterPro IPR002655 Acyl-CoA oxidase, C-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Protein Ontology PR:000003643 peroxisomal acyl-coenzyme A oxidase 2
References (Earliest) J:67589 Huyghe S, et al., Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J. 2001 Feb 1;353(Pt 3):673-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory