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Acox2
Gene Detail
Symbol

Name
ID
Acox2
acyl-Coenzyme A oxidase 2, branched chain
MGI:1934852
Feature Type
protein coding gene
Genetic Map
Chromosome 14
4.77 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:8225511-8259353 bp, - strand
From VEGA annotation of GRCm38

  33843 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74473  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: ACOX2
Protein SuperFamily: acyl-CoA oxidase
Gene Tree: Acox2

Human
homologs
ACOX2, acyl-CoA oxidase 2, branched chain
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8309
neXtProt AC: NX_Q99424

Human Synonyms: BCOX, BRCACOX, BRCOX, THCCox

Human Chr (Location): 3p14.3; chr3:58505136-58537348 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Acox2 interacts with 57 markers (Mir7-2, Mir7b, Mir9-1, ...)
Expression
Literature Summary: (4 records)
Data Summary: Results (68)    Tissues (55)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 53
Northern blot 15
cDNA source data(43)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase acox2    NEW 
Molecular
reagents
All nucleic(44) cDNA(43) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000035513 (Evidence)
Ensembl Gene Model ENSMUSG00000021751 (Evidence)
Entrez Gene 93732 (Evidence)
UniGene 28700
DFCI TC1581172
DoTS DT.537949, DT.94351156
NIA Mouse Gene Index U035228
EC 1.17.99.3
Consensus CDS Project CCDS36801.1
International Mouse Phenotyping Consortium Status Acox2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035513 VEGA Gene Model | MGI Sequence Detail 33843 C57BL/6J ±  kb
transcript OTTMUST00000090946 VEGA | MGI Sequence Detail 2441 Not Applicable 
polypeptide OTTMUSP00000050024 VEGA | MGI Sequence Detail 681 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(215 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
InterPro IPR012258 Acyl-CoA oxidase
InterPro IPR002655 Acyl-CoA oxidase, C-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
InterPro IPR029320 Acyl-coenzyme A oxidase, N-terminal
Protein Ontology PR:000003643 peroxisomal acyl-coenzyme A oxidase 2
References
(Earliest) J:67589 Huyghe S, et al., Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J. 2001 Feb 1;353(Pt 3):673-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory