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Acox2 Gene Detail
Summary
  • Symbol
    Acox2
  • Name
    acyl-Coenzyme A oxidase 2, branched chain
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934852
    NCBI Gene: 93732
Location & Maps
more
  • Sequence Map
    Chr14:8225511-8259353 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      33843 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 4.77 cM, cytoband A1
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ACOX2, acyl-CoA oxidase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ACOX2, acyl-CoA oxidase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BCOX, BRCACOX, BRCOX, THCCox
  • Links
    NCBI Gene ID: 8309
    neXtProt AC: NX_Q99424

  • Chr Location
    3p14.3; chr3:58505136-58537348 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
  • All Mutations and Alleles
    3
  • Endonuclease-mediated
    1
  • Targeted
    2
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    26
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    68
  • Tissues
    55
  • cDNA Data
    43
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035513 VEGA Gene Model | MGI Sequence Detail 33843 C57BL/6J ±  kb
transcript OTTMUST00000090946 VEGA | MGI Sequence Detail 2441 Not Applicable  
polypeptide OTTMUSP00000050024 VEGA | MGI Sequence Detail 681 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    214 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000003643 peroxisomal acyl-coenzyme A oxidase 2
  • EC
    1.17.99.3
  • InterPro Domains
    IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
    IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
    IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
    IPR012258 Acyl-CoA oxidase
    IPR002655 Acyl-CoA oxidase, C-terminal
    IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
    IPR029320 Acyl-coenzyme A oxidase, N-terminal
Molecular
Reagents
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  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:67589 Huyghe S, et al., Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J. 2001 Feb 1;353(Pt 3):673-80
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory