About   Help   FAQ
Tepsin Gene Detail
Summary
  • Symbol
    Tepsin
  • Name
    TEPSIN, adaptor related protein complex 4 accessory protein
  • Synonyms
    2410002I01Rik, Enthd2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926027
    NCBI Gene: 78777
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:119981357-119989557 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 83.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926027
 protein coding gene Chr11:119981348-119989675 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019490
 protein coding gene Chr11:124525300-124533500 (-)
A/J MGP_AJ_G0019458
 protein coding gene Chr11:118993915-119002115 (-)
AKR/J MGP_AKRJ_G0019428
 protein coding gene Chr11:122572088-122580288 (-)
BALB/cJ MGP_BALBcJ_G0019433
 protein coding gene Chr11:119350517-119358717 (-)
C3H/HeJ MGP_C3HHeJ_G0019239
 protein coding gene Chr11:122895314-122903565 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019882
 protein coding gene Chr11:128298492-128308359 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017507
 protein coding gene Chr11:115998327-116008280 (-)
CAST/EiJ MGP_CASTEiJ_G0018793
 protein coding gene Chr11:124377246-124385408 (-)
CBA/J MGP_CBAJ_G0019210
 protein coding gene Chr11:133313217-133321280 (-)
DBA/2J MGP_DBA2J_G0019322
 protein coding gene Chr11:118359888-118368099 (-)
FVB/NJ MGP_FVBNJ_G0019314
 protein coding gene Chr11:118049766-118059893 (-)
LP/J MGP_LPJ_G0019394
 protein coding gene Chr11:124834905-124843120 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019347
 protein coding gene Chr11:132176065-132184287 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019921
 protein coding gene Chr11:123255815-123264015 (-)
PWK/PhJ MGP_PWKPhJ_G0018559
 protein coding gene Chr11:119788465-119796822 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018351
 protein coding gene Chr11:123025784-123033961 (-)
WSB/EiJ MGP_WSBEiJ_G0018845
 protein coding gene Chr11:123252969-123262300 (-)



Homology
more
  • Human Ortholog
    TEPSIN, TEPSIN adaptor related protein complex 4 accessory protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEPSIN, TEPSIN adaptor related protein complex 4 accessory protein
  • Synonyms
    C17orf56, ENTHD2
  • Links
    NCBI Gene ID: 146705
    neXtProt AC: NX_Q96N21
    UniProt: Q96N21

  • Chr Location
    17q25.3; chr17:81228277-81239091 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    32
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025377 Ensembl Gene Model | MGI Sequence Detail 8201 C57BL/6J ±  kb
transcript ENSMUST00000093901 Ensembl | MGI Sequence Detail 2770 Not Applicable  
polypeptide ENSMUSP00000091428 Ensembl | MGI Sequence Detail 573 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory