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Itih5 Gene Detail
Summary
  • Symbol
    Itih5
  • Name
    inter-alpha (globulin) inhibitor H5
  • Synonyms
    4631408O11Rik, 5430408M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925751
    NCBI Gene: 209378
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:10153571-10256529 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 6.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    599 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925751
protein coding gene Chr2:10153536-10256529 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025340
protein coding gene Chr2:7507254-7606089 (+)
A/J MGP_AJ_G0025317
protein coding gene Chr2:7173228-7273602 (+)
AKR/J MGP_AKRJ_G0025286
protein coding gene Chr2:7410956-7510312 (+)
BALB/cJ MGP_BALBcJ_G0025313
protein coding gene Chr2:7176142-7278042 (+)
C3H/HeJ MGP_C3HHeJ_G0025073
protein coding gene Chr2:7358366-7461220 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025755
protein coding gene Chr2:7699693-7808299 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023169
protein coding gene Chr2:6685266-6786417 (+)
CAST/EiJ MGP_CASTEiJ_G0024536
protein coding gene Chr2:7384374-7491545 (+)
CBA/J MGP_CBAJ_G0025052
protein coding gene Chr2:8019920-8132570 (+)
DBA/2J MGP_DBA2J_G0025184
protein coding gene Chr2:7104477-7204689 (+)
FVB/NJ MGP_FVBNJ_G0025146
protein coding gene Chr2:7048472-7145136 (+)
LP/J MGP_LPJ_G0025270
protein coding gene Chr2:7385461-7488313 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025178
protein coding gene Chr2:7988446-8087339 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025813
protein coding gene Chr2:7360244-7464030 (+)
PWK/PhJ MGP_PWKPhJ_G0024287
protein coding gene Chr2:7090816-7192999 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024087
protein coding gene Chr2:7348911-7447183 (+)
WSB/EiJ MGP_WSBEiJ_G0024606
protein coding gene Chr2:7450838-7548267 (+)



Homology
more
  • Human Ortholog
    ITIH5, inter-alpha-trypsin inhibitor heavy chain 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ITIH5, inter-alpha-trypsin inhibitor heavy chain 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ITI-HC5, PP14776
  • Links
    NCBI Gene ID: 80760
    neXtProt AC: NX_Q86UX2
    UniProt: Q86UX2

  • Chr Location
    10p14; chr10:7559270-7666998 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025780 Ensembl Gene Model | MGI Sequence Detail 102959 C57BL/6J ±  kb
transcript ENSMUST00000026886 Ensembl | MGI Sequence Detail 7900 Not Applicable  
polypeptide ENSMUSP00000026886 Ensembl | MGI Sequence Detail 952 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913943
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:231595 Gurdziel K, et al., Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory