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Nkrf
Gene Detail
Symbol

Name
ID
Nkrf
NF-kappaB repressing factor
MGI:1924536
Synonyms
9430034D17Rik
Feature Type
protein coding gene
Genetic Map
Chromosome X
21.30 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:36887540-36902899 bp, - strand
From VEGA annotation of GRCm38

  15360 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84816  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NKRF
Gene Tree: Nkrf

Human
homologs
NKRF, NFKB repressing factor
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55922
neXtProt AC: NX_O15226

Human Synonyms: ITBA4, NRF

Human Chr (Location): Xq24; chrX:119588337-119606435 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(3) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous female and hemizygous male null mice are viable and fertile with normal inflammatory responses, response to infection, peripheral blood cell populations and skin morphology.
 
Interactions
Nkrf interacts with 294 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of transcription, DNA-templated, regulation of transcription, DNA-templated, ...
Component endoplasmic reticulum, nucleolus, ...
Function DNA binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (119)    Tissues (110)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 119
cDNA source data(35)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nkrf    NEW 
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(35)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000017111 (Evidence)
Ensembl Gene Model ENSMUSG00000044149 (Evidence)
Entrez Gene 77286 (Evidence)
UniGene 21649
DFCI TC1583442, TC1601495, TC1608008
DoTS DT.101350244, DT.40136299, DT.487166
NIA Mouse Gene Index U041237
Consensus CDS Project CCDS30065.1
International Mouse Phenotyping Consortium Status Nkrf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017111 VEGA Gene Model | MGI Sequence Detail 15360 C57BL/6J ±  kb
transcript OTTMUST00000041435 VEGA | MGI Sequence Detail 3268 Not Applicable 
polypeptide OTTMUSP00000018595 VEGA | MGI Sequence Detail 690 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014720 Double-stranded RNA-binding-like domain
InterPro IPR000467 G-patch domain
InterPro IPR001374 Single-stranded nucleic acid binding R3H
Protein Ontology PR:000011237 NF-kappa-B-repressing factor
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2148002, MGI:2148062

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory