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Bicd2 Gene Detail
Summary
  • Symbol
    Bicd2
  • Name
    bicaudal D homolog 2 (Drosophila)
  • Synonyms
    0610027D24Rik, 1110005D12Rik, mKIAA0699
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924145
    NCBI Gene: 76895
  • Gene Overview
    MyGene.info: BICD2
Location & Maps
more
  • Sequence Map
    Chr13:49341549-49387025 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      45477 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 25.22 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    BICD2, BICD cargo adaptor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BICD2, BICD cargo adaptor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA526D8.1, SMALED2
  • Links
    NCBI Gene ID: 23299
    neXtProt AC: NX_Q8TD16
    UniProt: Q8TD16

  • Chr Location
    9q22.31; chr9:92711363-92764841 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9070
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BICD2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    36 phenotypes from 2 alleles in 2 genetic backgrounds
    8 images
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037933 Ensembl Gene Model | MGI Sequence Detail 45477 C57BL/6J ±  kb
transcript ENSMUST00000048544 Ensembl | MGI Sequence Detail 6351 Not Applicable  
polypeptide ENSMUSP00000039394 Ensembl | MGI Sequence Detail 851 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    167 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 140
    cDNA 140

    Microarray probesets 10
Other
Accession IDs
less
MGI:1915741
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:236950 Matsuto M, et al., Reconstitution of the targeting of Rab6A to the Golgi apparatus in semi-intact HeLa cells: A role of BICD2 in stabilizing Rab6A on Golgi membranes and a concerted role of Rab6A/BICD2 interactions in Golgi-to-ER retrograde transport. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2592-609

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory