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Arpc2
Gene Detail
Symbol

Name
ID
Arpc2
actin related protein 2/3 complex, subunit 2
MGI:1923959
Synonyms
2210023N03Rik, p34-Arc
Feature Type
protein coding gene
Genetic Map
Chromosome 1
38.49 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:74236084-74268209 bp, + strand
From VEGA annotation of GRCm38

  32126 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4187  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ARPC2
Protein SuperFamily: Actin-related protein 2/3 complex subunit 2
Gene Tree: Arpc2

Human
homologs
ARPC2, actin related protein 2/3 complex, subunit 2, 34kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10109
neXtProt AC: NX_O15144

Human Synonyms: ARC34, p34-Arc, PNAS-139, PRO2446

Human Chr (Location): 2q36.1; chr2:218217094-218254348 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(73) : Gene trapped(70) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Arpc2 interacts with 116 markers (Mir1a-1, Mir1a-2, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (4)    Tissues (1)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
cDNA source data(231)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase arpc2 ; ZFIN arpc2    NEW 
Molecular
reagents
All nucleic(232) cDNA(232)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000016449 (Evidence)
Ensembl Gene Model ENSMUSG00000006304 (Evidence)
Entrez Gene 76709 (Evidence)
UniGene 337038
DFCI TC1584161, TC1734643, TC1706495
DoTS DT.110549266, DT.101382715, DT.101200628, DT.94237560, DT.496614
NIA Mouse Gene Index U000441
Consensus CDS Project CCDS35612.1
International Mouse Phenotyping Consortium Status Arpc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016449 VEGA Gene Model | MGI Sequence Detail 32126 C57BL/6J ±  kb
transcript OTTMUST00000041972 VEGA | MGI Sequence Detail 1404 Not Applicable 
polypeptide OTTMUSP00000018874 VEGA | MGI Sequence Detail 300 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(225 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007188 ARP2/3 complex, 34kDa subunit (p34-Arc)
Protein Ontology PR:000004310 actin-related protein 2/3 complex subunit 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:185589 Maritzen T, et al., Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10382-7
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory