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Lhpp Gene Detail
Summary
  • Symbol
    Lhpp
  • Name
    phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  • Synonyms
    2310007H09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923679
    NCBI Gene: 76429
Location & Maps
more
  • Sequence Map
    Chr7:132610638-132706420 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      95783 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 76.30 cM, cytoband F4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LHPP, phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LHPP, phospholysine phosphohistidine inorganic pyrophosphate phosphatase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HDHD2B
  • Links
    NCBI Gene ID: 64077
    neXtProt AC: NX_Q9H008

  • Chr Location
    10q26.13; chr10:124461772-124614141 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41469
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: LHPP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024032 VEGA Gene Model | MGI Sequence Detail 95783 C57BL/6J ±  kb
transcript OTTMUST00000058759 VEGA | MGI Sequence Detail 1612 Not Applicable  
polypeptide OTTMUSP00000028512 VEGA | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    523 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009790 phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  • EC
  • InterPro Domains
    IPR023214 HAD-like domain
    IPR006357 HAD-superfamily hydrolase, subfamily IIA
    IPR006355 HAD-superfamily hydrolase, subfamily IIA, hypothetical 2
    IPR023215 Nitrophenylphosphatase-like domain
Molecular
Reagents
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  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory