About   Help   FAQ
Lhpp Gene Detail
Summary
  • Symbol
    Lhpp
  • Name
    phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  • Synonyms
    2310007H09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923679
    NCBI Gene: 76429
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:132610638-132706420 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 76.30 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    523 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923679
protein coding gene Chr7:132610614-132706420 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033114
protein coding gene Chr7:137311266-137407257 (+)
A/J MGP_AJ_G0033096
protein coding gene Chr7:133530408-133625531 (+)
AKR/J MGP_AKRJ_G0033028
protein coding gene Chr7:137092791-137189936 (+)
BALB/cJ MGP_BALBcJ_G0033097
protein coding gene Chr7:133212363-133309458 (+)
C3H/HeJ MGP_C3HHeJ_G0032811
protein coding gene Chr7:136925909-137024843 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033608
protein coding gene Chr7:142545285-142643211 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030579
protein coding gene Chr7:134809945-134906679 (+)
CAST/EiJ MGP_CASTEiJ_G0032141
protein coding gene Chr7:128824698-128938160 (+)
CBA/J MGP_CBAJ_G0032784
protein coding gene Chr7:147371083-147470807 (+)
DBA/2J MGP_DBA2J_G0032936
protein coding gene Chr7:131542205-131639816 (+)
FVB/NJ MGP_FVBNJ_G0032889
protein coding gene Chr7:131366828-131476960 (+)
LP/J MGP_LPJ_G0033030
protein coding gene Chr7:138820780-138926770 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032921
protein coding gene Chr7:148300625-148401434 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033628
protein coding gene Chr7:136071836-136173021 (+)
PWK/PhJ MGP_PWKPhJ_G0031847
protein coding gene Chr7:124564396-124662662 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031693
protein coding gene Chr7:122866314-122968108 (+)
WSB/EiJ MGP_WSBEiJ_G0032252
protein coding gene Chr7:136980736-137083572 (+)



Homology
more
  • Human Ortholog
    LHPP, phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LHPP, phospholysine phosphohistidine inorganic pyrophosphate phosphatase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HDHD2B
  • Links
    NCBI Gene ID: 64077
    neXtProt AC: NX_Q9H008
    UniProt: Q9H008

  • Chr Location
    10q26.13; chr10:124461772-124614141 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41469
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LHPP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030946 Ensembl Gene Model | MGI Sequence Detail 95783 C57BL/6J ±  kb
transcript ENSMUST00000033241 Ensembl | MGI Sequence Detail 1612 Not Applicable  
polypeptide ENSMUSP00000033241 Ensembl | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory