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Ercc6l2
Gene Detail
Symbol

Name
ID
Ercc6l2
excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
MGI:1923501
Synonyms
0610007P08Rik, 1700019D06Rik, 9330134C04Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
33.10 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:63815240-63900302 bp, + strand
From VEGA annotation of GRCm38

  85063 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32564  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 zebrafish

HCOP human homology predictions: ERCC6L2
Gene Tree: Ercc6l2

Human
homologs
ERCC6L2, excision repair cross-complementation group 6-like 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 375748
neXtProt AC: NX_Q5T890

Human Synonyms: BMFS2, C9orf102, RAD26L, SR278

Human Chr (Location): 9q22.32; chr9:95875618-96120476 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ERCC6L2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Ercc6l2 interacts with 292 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cellular response to DNA damage stimulus, DNA repair
Component cytoplasm, cytoskeleton, ...
Function ATP binding, ATP-dependent helicase activity, ...
External Resources: FuncBase
Expression
cDNA source data(80)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ercc6l2    NEW 
Molecular
reagents
All nucleic(80) cDNA(80)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000026114 (Evidence)
Ensembl Gene Model ENSMUSG00000021470 (Evidence)
Entrez Gene 76251 (Evidence)
UniGene 186610
DFCI TC1617467, TC1610738, TC1606338, TC1598441, TC1603577, TC1591409, TC1584976, TC1588720, TC1582621
NIA Mouse Gene Index U043344
EC 3.6.4.-
Consensus CDS Project CCDS26593.1, CCDS36701.1
International Mouse Phenotyping Consortium Status Ercc6l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026114 VEGA Gene Model | MGI Sequence Detail 85063 C57BL/6J ±  kb
transcript OTTMUST00000087277 VEGA | MGI Sequence Detail 3436 Not Applicable 
polypeptide OTTMUSP00000047349 VEGA | MGI Sequence Detail 842 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(8) UniProt(10)
Polymorphisms
SNPs within 2kb(574 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000330 SNF2-related
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)
Other
accession IDs
MGI:1916653, MGI:3689365

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory