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Gns Gene Detail
Summary
  • Symbol
    Gns
  • Name
    glucosamine (N-acetyl)-6-sulfatase
  • Synonyms
    2610016K11Rik, G6S
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922862
    NCBI Gene: 75612
Location & Maps
more
  • Sequence Map
    Chr10:121365090-121397245 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32156 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 69.62 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GNS, glucosamine (N-acetyl)-6-sulfatase
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNS, glucosamine (N-acetyl)-6-sulfatase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    G6S
  • Links
    NCBI Gene ID: 2799
    neXtProt AC: NX_P15586

  • Chr Location
    12q14.3; chr12:64713442-64759446 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human GNS associations

Human Disease Mouse Models
       Mucopolysaccharidosis, Type Iiid; MPS3D   OMIM: 252940
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    8
  • Gene trapped
    4
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034707 Ensembl Gene Model | MGI Sequence Detail 32156 C57BL/6J ±  kb
transcript ENSMUST00000040344 Ensembl | MGI Sequence Detail 3855 Not Applicable  
polypeptide ENSMUSP00000043167 Ensembl | MGI Sequence Detail 544 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    486 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 26
    Other 1

    Microarray probesets 5
Other
Accession IDs
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MGI:2143761, MGI:2143948, MGI:2143956
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory