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Tspan17 Gene Detail
Summary
  • Symbol
    Tspan17
  • Name
    tetraspanin 17
  • Synonyms
    2210021G21Rik, Fbxo23, Tm4sf17
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921507
    NCBI Gene: 74257
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:54789377-54796776 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 29.41 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    62 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921507
protein coding gene Chr13:54789351-54796776 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020581
protein coding gene Chr13:54214459-54221858 (+)
A/J MGP_AJ_G0020535
protein coding gene Chr13:52216279-52223679 (+)
AKR/J MGP_AKRJ_G0020513
protein coding gene Chr13:53754448-53761835 (+)
BALB/cJ MGP_BALBcJ_G0020531
protein coding gene Chr13:52454807-52462207 (+)
C3H/HeJ MGP_C3HHeJ_G0020330
protein coding gene Chr13:53576215-53583615 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020965
protein coding gene Chr13:55869353-55876752 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018547
protein coding gene Chr13:50206846-50214244 (+)
CAST/EiJ MGP_CASTEiJ_G0019844
protein coding gene Chr13:53661865-53669288 (+)
CBA/J MGP_CBAJ_G0020290
protein coding gene Chr13:57992881-58000281 (+)
DBA/2J MGP_DBA2J_G0020413
protein coding gene Chr13:51783568-51790967 (+)
FVB/NJ MGP_FVBNJ_G0020392
protein coding gene Chr13:51241469-51248868 (+)
LP/J MGP_LPJ_G0020489
protein coding gene Chr13:54482447-54489838 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020421
protein coding gene Chr13:57504217-57511604 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021008
protein coding gene Chr13:53347121-53354520 (+)
PWK/PhJ MGP_PWKPhJ_G0019600
protein coding gene Chr13:51775636-51783024 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019427
protein coding gene Chr13:52274107-52281483 (+)
WSB/EiJ MGP_WSBEiJ_G0019906
protein coding gene Chr13:53681150-53688536 (+)



Homology
more
  • Human Ortholog
    TSPAN17, tetraspanin 17
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TSPAN17, tetraspanin 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBX23, FBXO23, TM4SF17
  • Links
    NCBI Gene ID: 26262
    neXtProt AC: NX_Q96FV3
    UniProt: Q96FV3

  • Chr Location
    5q35.2; chr5:176647387-176659058 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025875 Ensembl Gene Model | MGI Sequence Detail 7400 C57BL/6J ±  kb
transcript ENSMUST00000131692 Ensembl | MGI Sequence Detail 1048 Not Applicable  
polypeptide ENSMUSP00000115287 Ensembl | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145183
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:209476 Haining EJ, et al., The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression. J Biol Chem. 2012 Nov 16;287(47):39753-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory