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Zdhhc16 Gene Detail
Summary
  • Symbol
    Zdhhc16
  • Name
    zinc finger, DHHC domain containing 16
  • Synonyms
    1500015N03Rik, Abl-philin 2, Ablphilin 2, APH2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921418
    NCBI Gene: 74168
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:41921919-41932543 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 35.48 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921418
protein coding gene Chr19:41921884-41932543 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025132
protein coding gene Chr19:41236789-41248035 (+)
A/J MGP_AJ_G0025109
protein coding gene Chr19:39254556-39265019 (+)
AKR/J MGP_AKRJ_G0025077
protein coding gene Chr19:40544135-40555865 (+)
BALB/cJ MGP_BALBcJ_G0025103
protein coding gene Chr19:39313447-39324162 (+)
C3H/HeJ MGP_C3HHeJ_G0024863
protein coding gene Chr19:40694150-40704840 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025546
protein coding gene Chr19:42311637-42322125 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022960
protein coding gene Chr19:38608645-38618615 (+)
CAST/EiJ MGP_CASTEiJ_G0024328
protein coding gene Chr19:40365113-40382549 (+)
CBA/J MGP_CBAJ_G0024843
protein coding gene Chr19:44373831-44387547 (+)
DBA/2J MGP_DBA2J_G0024975
protein coding gene Chr19:39105028-39115670 (+)
FVB/NJ MGP_FVBNJ_G0024936
protein coding gene Chr19:38879694-38890097 (+)
LP/J MGP_LPJ_G0025061
protein coding gene Chr19:41230844-41241263 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024967
protein coding gene Chr19:44000836-44012773 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025604
protein coding gene Chr19:40581780-40593384 (+)
PWK/PhJ MGP_PWKPhJ_G0024077
protein coding gene Chr19:38979879-38992172 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023881
protein coding gene Chr19:39326209-39336447 (+)
WSB/EiJ MGP_WSBEiJ_G0024398
protein coding gene Chr19:40735646-40746159 (+)



Homology
more
  • Human Ortholog
    ZDHHC16, zinc finger DHHC-type palmitoyltransferase 16
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDHHC16, zinc finger DHHC-type palmitoyltransferase 16
  • Synonyms
    APH2, DHHC-16
  • Links
    NCBI Gene ID: 84287
    neXtProt AC: NX_Q969W1
    UniProt: Q969W1

  • Chr Location
    10q24.1; chr10:97446170-97457370 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display prenatal and neonatal lethality with bradycardia, abnormal heart morphology and eye defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025157 Ensembl Gene Model | MGI Sequence Detail 10625 C57BL/6J ±  kb
    transcript ENSMUST00000026154 Ensembl | MGI Sequence Detail 1821 Not Applicable  
    polypeptide ENSMUSP00000026154 Ensembl | MGI Sequence Detail 361 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 5
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory