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F13a1
Gene Detail
 Symbol
Name
ID
F13a1
coagulation factor XIII, A1 subunit
MGI:1921395
Synonyms 1200014I03Rik, Factor XIIIA
Feature Type protein coding gene
Genetic Map
Chromosome 13
14.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:36867178-37050244 bp, - strand
From NCBI annotation of GRCm38

  183067 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20077  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: TGM_EBP42
Gene Tree: F13a1

Human
homologs
Human Homolog F13A1, coagulation factor XIII, A1 polypeptide
NCBI Gene ID 2162
neXtProt AC  NX_P00488
Human Synonyms  F13A
Human Chr (Location)  6p25.3-p24.3; chr6:6144078-6321013 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human F13A1
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
 
Homozygous mutant mice exhibit bleeding symptoms, increased lethality, and impaired fertility.
 
Human Diseases Modeled Using Mouse F13a1 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(1)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process blood coagulation, hemostasis, ...
Component blood microparticle, cytoplasm, ...
Function metal ion binding, protein-glutamine gamma-glutamyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (97)    Tissues (95)    Images (6)
Theiler Stages: 22, 26
Assay TypeResults
Immunohistochemistry 3
RNA in situ 94
cDNA source data(64)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(64) cDNA(64)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000039109 (Evidence)
Entrez Gene74145 (Evidence)
UniGene235105
DFCITC1575865, TC1609482, TC1761399
DoTSDT.101354119, DT.101371012, DT.101734866, DT.87028181, DT.91335215, DT.91402718
NIA Mouse Gene IndexU034690
EC2.3.2.13
Consensus CDS ProjectCCDS26456.1
International Mouse Knockout Project StatusF13a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 74145 NCBI Gene Model | MGI Sequence Detail 183067 C57BL/6J ±  kb
transcript NM_028784 RefSeq | MGI Sequence Detail 3879 Not Specified 
polypeptide Q8BH61 UniProt | EBI | MGI Sequence Detail 732 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(4) UniProt(7)
Polymorphisms SNPs within 2kb(1213 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR023608 Protein-glutamine gamma-glutamyltransferase, eukaryota
InterPro IPR013808 Transglutaminase, conserved site
InterPro IPR008958 Transglutaminase, C-terminal
InterPro IPR002931 Transglutaminase-like
InterPro IPR001102 Transglutaminase, N-terminal
InterPro IPR000738 WHEP-TRS
Protein Ontology PR:000007297 coagulation factor XIII A chain
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(40)
Other
accession IDs
MGI:2145250

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory