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Rd3
Gene Detail
 Symbol
Name
ID
Rd3
retinal degeneration 3
MGI:1921273
Synonyms 3322402L07Rik, rd3, rd-3
Feature Type protein coding gene
Genetic Map
Chromosome 1
97.09 cM, cytoband H6
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr1:191977373-191988282 bp, + strand
From VEGA annotation of GRCm38

  10910 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11373  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rd3

Human
homologs
Human Homolog RD3, retinal degeneration 3
NCBI Gene ID 343035
neXtProt AC  NX_Q7Z3Z2
Human Synonyms  C1orf36, LCA12
Human Chr (Location)  1q32.3; chr1:211476522-211492917 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human RD3
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Spontaneous(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a spontaneous mutation exhibit retinal degeneration, beginning at 3 weeks of age, characterized by complete loss of photoreceptor rod cells by 5 weeks, and cones by 8 weeks.
 
Interactions
Rd3 interacts with 269 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process response to stimulus, retina development in camera-type eye, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (47)    Tissues (8)    Images (26)
Theiler Stages: 23, 27, 28
Assay TypeResults
RNA in situ 47
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(23)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000042235 (Evidence)
Ensembl Gene ModelENSMUSG00000049353 (Evidence)
Entrez Gene74023 (Evidence)
UniGene274393
DFCITC1584970, TC1604759, TC1615224, TC1630611
DoTSDT.101282900, DT.87056734, DT.91553149, DT.94176082
NIA Mouse Gene IndexU001299
Consensus CDS ProjectCCDS15626.2
International Mouse Knockout Project StatusRd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042235 VEGA Gene Model | MGI Sequence Detail 10910 C57BL/6J ±  kb
transcript OTTMUST00000112819 VEGA | MGI Sequence Detail 3704 Not Applicable 
polypeptide OTTMUSP00000063191 VEGA | MGI Sequence Detail 195 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(110 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000013846 protein RD3
References (Earliest) J:4364 Bell JR, et al., Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene [published erratum appears in Genomics 1993 Sep;17(3):800]. Genomics. 1993 Apr;16(1):123-31
(Latest) J:202634 Cheng CL, et al., Changes in gene expression associated with retinal degeneration in the rd3 mouse. Mol Vis. 2013;19:955-69
All references(44)
Other
accession IDs
MGD-MRK-13810, MGD-MRK-13813, MGI:97884

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory