Rd3
Gene Detail

Symbol Name ID

Rd3 retinal degeneration 3 MGI:1921273

Synonyms

3322402L07Rik, rd3, rd-3

Feature Type

protein coding gene

Genetic Map

Chromosome 1

97.09 cM, cytoband H6
Detailed Genetic Map ± 1 cM


Mapping data(10)

Sequence Map

Chr1:191978251-191986392 bp, + strand From VEGA annotation of GRCm38   8142 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11373  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rd3

Human homologs

Human Homolog		RD3, retinal degeneration 3
NCBI Gene ID		343035
neXtProt AC		NX_Q7Z3Z2
Human Synonyms		C1orf36, LCA12
Human Chr (Location)		1q32.3; chr1:211649864-211666259 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RD3

Alleles and phenotypes

All alleles(2) : Gene trapped(1) Spontaneous(1)
 

Homozygotes for a spontaneous mutation exhibit retinal degeneration, beginning at 3 weeks of age, characterized by complete loss of photoreceptor rod cells by 5 weeks, and cones by 8 weeks.

 

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process

response to stimulus, retina development in camera-type eye, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (47)    Tissues (7)    Images (26)
Theiler Stages: 23, 28

Assay Type	Results
RNA in situ	47

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) cDNA(23)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000042235 (Evidence)
Ensembl Gene Model	ENSMUSG00000049353 (Evidence)
Entrez Gene	74023 (Evidence)
UniGene	274393
DFCI	TC1584970, TC1604759, TC1615224, TC1630611
DoTS	DT.101282900, DT.87056734, DT.91553149, DT.94176082
NIA Mouse Gene Index	U001299
Consensus CDS Project	CCDS15626.2
International Mouse Knockout Project Status	Rd3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000042235	VEGA Gene Model | MGI Sequence Detail	8142	C57BL/6J
transcript	OTTMUST00000111011	VEGA | MGI Sequence Detail	1970	Not Applicable
polypeptide	OTTMUSP00000062030	VEGA | MGI Sequence Detail	105	Not Applicable

All sequences(35) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(70 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000013846	protein RD3

References

(Earliest) J:4364 Bell JR, et al., Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene [published erratum appears in Genomics 1993 Sep;17(3):800]. Genomics. 1993 Apr;16(1):123-31
(Latest) J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
All references(42)

Other accession IDs

MGD-MRK-13810, MGD-MRK-13813, MGI:97884