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Kif2c Gene Detail
Summary
  • Symbol
    Kif2c
  • Name
    kinesin family member 2C
  • Synonyms
    4930402F02Rik, MGC:11883
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921054
    NCBI Gene: 73804
  • Gene Overview
    MyGene.info: KIF2C
Location & Maps
more
  • Sequence Map
    Chr4:117159639-117182639 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23001 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.42 cM, cytoband D1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    KIF2C, kinesin family member 2C
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KIF2C, kinesin family member 2C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT139, KNSL6, MCAK
  • Links
    NCBI Gene ID: 11004
    neXtProt AC: NX_Q99661

  • Chr Location
    1p34.1; chr1:44739712-44767767 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    26
  • Chemically induced (other)
    2
  • Gene trapped
    18
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Kif2c
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009919 VEGA Gene Model | MGI Sequence Detail 23001 C57BL/6J ±  kb
transcript OTTMUST00000023036 VEGA | MGI Sequence Detail 2842 Not Applicable  
polypeptide OTTMUSP00000010510 VEGA | MGI Sequence Detail 721 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    233 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-28119, MGI:104825
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:28401 Bettenhausen B, et al., Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
  • Latest
    J:212449 Shimizu Y, et al., Effects of the KIF2C neck peptide on microtubules: lateral disintegration of microtubules and beta-structure formation. FEBS J. 2013 Apr;280(7):1681-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory