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Kif2c Gene Detail
Summary
  • Symbol
    Kif2c
  • Name
    kinesin family member 2C
  • Synonyms
    4930402F02Rik, MGC:11883
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921054
    NCBI Gene: 73804
  • Gene Overview
    MyGene.info: KIF2C
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117159633-117182624 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.42 cM, cytoband D1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    233 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921054
protein coding gene Chr4:117159633-117182639 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028647
protein coding gene Chr4:118122969-118147351 (-)
A/J MGP_AJ_G0028608
protein coding gene Chr4:113569632-113594325 (-)
AKR/J MGP_AKRJ_G0028558
protein coding gene Chr4:116050923-116073597 (-)
BALB/cJ MGP_BALBcJ_G0028629
protein coding gene Chr4:114199750-114222708 (-)
C3H/HeJ MGP_C3HHeJ_G0028343
protein coding gene Chr4:117616519-117640829 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029070
protein coding gene Chr4:122684434-122712407 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026354
protein coding gene Chr4:107611893-107634451 (-)
CAST/EiJ MGP_CASTEiJ_G0027777
protein coding gene Chr4:114834139-114858135 (-)
CBA/J MGP_CBAJ_G0028310
protein coding gene Chr4:126038045-126064237 (-)
DBA/2J MGP_DBA2J_G0028458
protein coding gene Chr4:114205891-114229066 (-)
FVB/NJ MGP_FVBNJ_G0028426
protein coding gene Chr4:112706051-112729404 (-)
LP/J MGP_LPJ_G0028560
protein coding gene Chr4:118303526-118329227 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028453
protein coding gene Chr4:130985291-131015869 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029107
protein coding gene Chr4:117199166-117224848 (-)
PWK/PhJ MGP_PWKPhJ_G0027503
protein coding gene Chr4:111004165-111029259 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027326
protein coding gene Chr4:113497329-113519580 (-)
WSB/EiJ MGP_WSBEiJ_G0027856
protein coding gene Chr4:117070146-117105854 (-)



Homology
more
  • Human Ortholog
    KIF2C, kinesin family member 2C
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KIF2C, kinesin family member 2C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT139, KNSL6, MCAK
  • Links
    NCBI Gene ID: 11004
    neXtProt AC: NX_Q99661
    UniProt: Q99661

  • Chr Location
    1p34.1; chr1:44739704-44767767 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73804 NCBI Gene Model | MGI Sequence Detail 22992 C57BL/6J ±  kb
transcript NM_134471 RefSeq | MGI Sequence Detail 2840 C57BL/6  
polypeptide Q922S8 UniProt | EBI | MGI Sequence Detail 721 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-28119, MGI:104825
References
more
  • Summaries
    All 48
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:28401 Bettenhausen B, et al., Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory