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Dmrtc2
Gene Detail
 Symbol
Name
ID
Dmrtc2
doublesex and mab-3 related transcription factor like family C2
MGI:1918491
Synonyms 4933432E21Rik, Dmrt7
Feature Type protein coding gene
Genetic Map
Chromosome 7
13.33 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:24870057-24877651 bp, + strand
From VEGA annotation of GRCm38

  7595 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75260  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Dmrtc2

Human
homologs
Human Homolog DMRTC2, DMRT-like family C2
NCBI Gene ID 63946
neXtProt AC  NX_Q8IXT2
Human Chr (Location)  19q13.2; chr19:41845001-41852330 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Males homozygous for a targeted allele are sterile.
 
Phenotype Images(1)
Interactions
Dmrtc2 interacts with 96 markers (Mir1b, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cell differentiation, male meiosis I, ...
Component nucleus, XY body
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (165)    Tissues (136)    Images (12)
Theiler Stages: 13, 15, 17, 19, 20, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 137
RT-PCR 28
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(10) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000024043 (Evidence)
Ensembl Gene ModelENSMUSG00000011349 (Evidence)
Entrez Gene71241 (Evidence)
UniGene66855
DFCITC1588623
DoTSDT.55283401
NIA Mouse Gene IndexU007809
Consensus CDS ProjectCCDS20965.1
International Mouse Knockout Project StatusDmrtc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024043 VEGA Gene Model | MGI Sequence Detail 7595 C57BL/6J ±  kb
transcript OTTMUST00000058782 VEGA | MGI Sequence Detail 1619 Not Applicable 
polypeptide OTTMUSP00000028526 VEGA | MGI Sequence Detail 370 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(8) UniProt(1)
Polymorphisms SNPs within 2kb(22 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001275 DM DNA-binding
InterPro IPR026607 DMRT/protein doublesex/protein male abnormal 3
Protein Ontology PR:000006549 doublesex- and mab-3-related transcription factor C2
References (Earliest) J:68323 Carninci P, et al., Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res. 2000 Oct;10(10):1617-30
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory