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Hsfy2 Gene Detail
Summary
  • Symbol
    Hsfy2
  • Name
    heat shock transcription factor, Y-linked 2
  • Synonyms
    4933413G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918316
    NCBI Gene: 71066
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:56636044-56637435 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 28.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918316
protein coding gene Chr1:56636044-56637451 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016037
protein coding gene Chr1:56424127-56425518 (-)
A/J MGP_AJ_G0016020
protein coding gene Chr1:54461267-54462658 (-)
AKR/J MGP_AKRJ_G0015976
protein coding gene Chr1:55910138-55911529 (-)
BALB/cJ MGP_BALBcJ_G0015975
protein coding gene Chr1:54499344-54500735 (-)
C3H/HeJ MGP_C3HHeJ_G0015807
protein coding gene Chr1:56191013-56192404 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016428
protein coding gene Chr1:58755398-58756789 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014149
protein coding gene Chr1:50451235-50452627 (-)
CAST/EiJ MGP_CASTEiJ_G0015389
protein coding gene Chr1:55451258-55452649 (-)
CBA/J MGP_CBAJ_G0015779
protein coding gene Chr1:60444484-60445875 (-)
DBA/2J MGP_DBA2J_G0015880
protein coding gene Chr1:53877080-53878471 (-)
FVB/NJ MGP_FVBNJ_G0015882
protein coding gene Chr1:53204614-53206005 (-)
LP/J MGP_LPJ_G0015952
protein coding gene Chr1:57297156-57298547 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015902
protein coding gene Chr1:63514972-63516363 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016475
protein coding gene Chr1:55902357-55903748 (-)
PWK/PhJ MGP_PWKPhJ_G0015175
protein coding gene Chr1:53208486-53209878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014956
protein coding gene Chr1:55490383-55491774 (-)
WSB/EiJ MGP_WSBEiJ_G0015452
protein coding gene Chr1:55570147-55571538 (-)



Homology
more
  • Human Ortholog
    HSFY1, heat shock transcription factor Y-linked 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    HSFY1, heat shock transcription factor Y-linked 1
    Orthology source: HomoloGene
  • Synonyms
    HSF2L, HSFY
  • Links
    NCBI Gene ID: 86614
    neXtProt AC: NX_Q96LI6
    UniProt: Q96LI6

  • Chr Location
    Yq11.222; chrY:18529679-18588963 (+)  GRCh38.p7

  • Human Ortholog
    HSFY2, heat shock transcription factor Y-linked 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSF2L, HSFY
  • Links
    NCBI Gene ID: 159119
    neXtProt AC: NX_Q96LI6
    UniProt: Q96LI6

  • Chr Location
    Yq11.222; chrY:18731440-18790733 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Hsfy2
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045336 Ensembl Gene Model | MGI Sequence Detail 1392 C57BL/6J ±  kb
transcript ENSMUST00000062085 Ensembl | MGI Sequence Detail 1392 Not Applicable  
polypeptide ENSMUSP00000049715 Ensembl | MGI Sequence Detail 392 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000232 Heat shock factor (HSF)-type, DNA-binding
    IPR027725 Heat shock transcription factor family
    IPR027730 Heat shock transcription factor, Y-linked
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
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  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory