About   Help   FAQ
Jhy Gene Detail
Summary
  • Symbol
    Jhy
  • Name
    junctional cadherin complex regulator
  • Synonyms
    4931429I11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918239
    NCBI Gene: 70989
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr9:40894849-40964118 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 21.68 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    643 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918239
protein coding gene Chr9:40894849-40966861 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034672
protein coding gene Chr9:39146974-39216400 (-)
A/J MGP_AJ_G0034652
protein coding gene Chr9:38135567-38200521 (-)
AKR/J MGP_AKRJ_G0034578
protein coding gene Chr9:38853834-38920481 (-)
BALB/cJ MGP_BALBcJ_G0034643
protein coding gene Chr9:37878826-37942331 (-)
C3H/HeJ MGP_C3HHeJ_G0034354
protein coding gene Chr9:39379951-39445427 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035166
protein coding gene Chr9:40391320-40459409 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032079
protein coding gene Chr9:37760832-37825825 (-)
CAST/EiJ MGP_CASTEiJ_G0033677
protein coding gene Chr9:39104665-39171663 (-)
CBA/J MGP_CBAJ_G0034327
protein coding gene Chr9:41778654-41847395 (-)
DBA/2J MGP_DBA2J_G0034486
protein coding gene Chr9:38068351-38132266 (-)
FVB/NJ MGP_FVBNJ_G0034426
protein coding gene Chr9:37292370-37356247 (-)
LP/J MGP_LPJ_G0034567
protein coding gene Chr9:39421882-39487576 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034470
protein coding gene Chr9:43830692-43895900 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035185
protein coding gene Chr9:38779203-38844762 (-)
PWK/PhJ MGP_PWKPhJ_G0033382
protein coding gene Chr9:37880587-37945293 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033218
protein coding gene Chr9:39006498-39077783 (-)
WSB/EiJ MGP_WSBEiJ_G0033790
protein coding gene Chr9:38806308-38870765 (-)



Homology
more
  • Human Ortholog
    JHY, junctional cadherin complex regulator
  • Vertebrate Orthologs
    8
  • Human Ortholog
    JHY, junctional cadherin complex regulator
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C11orf63
  • Links
    NCBI Gene ID: 79864
    neXtProt AC: NX_Q6NUN7
    UniProt: Q6NUN7

  • Chr Location
    11q24.1; chr11:122881640-122963862 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit hydrocephalus, domed cranium, ataxia, weight loss, enlarged lateral ventricle, neuodegeneration, abnormal brain ependymal motile cilium and premature death.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032023 Ensembl Gene Model | MGI Sequence Detail 69270 C57BL/6J ±  kb
    transcript ENSMUST00000034521 Ensembl | MGI Sequence Detail 3074 Not Applicable  
    polypeptide ENSMUSP00000034521 Ensembl | MGI Sequence Detail 770 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR027968 Jhy protein
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143374
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:253677 Muniz-Talavera H, et al., The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis. PLoS One. 2017;12(12):e0184957

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    12/11/2018
    MGI 6.13
    The Jackson Laboratory