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Wars2
Gene Detail
 Symbol
Name
ID
Wars2
tryptophanyl tRNA synthetase 2 (mitochondrial)
MGI:1917810
Synonyms 9430020O07Rik, TrpRS
Feature Type protein coding gene
Genetic Map
Chromosome 3
43.03 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:99141068-99239186 bp, + strand
From VEGA annotation of GRCm38

  98119 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5673  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: tryptophan-tRNA ligase
Gene Tree: Wars2

Human
homologs
Human Homolog WARS2, tryptophanyl tRNA synthetase 2, mitochondrial
NCBI Gene ID 10352
neXtProt AC  NX_Q9UGM6
Human Synonyms  TrpRS
Human Chr (Location)  1p12; chr1:119031216-119140788 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process translation, tRNA aminoacylation for protein translation, ...
Component cytoplasm, mitochondrion
Function aminoacyl-tRNA ligase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (9)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(33)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000006862 (Evidence)
Ensembl Gene ModelENSMUSG00000004233 (Evidence)
Entrez Gene70560 (Evidence)
UniGene316754
DFCITC1582420, TC1662996
DoTSDT.111054966, DT.55141637, DT.55270283
NIA Mouse Gene IndexU003628
EC6.1.1.2
Consensus CDS ProjectCCDS17672.1
International Mouse Knockout Project StatusWars2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006862 VEGA Gene Model | MGI Sequence Detail 98119 C57BL/6J ±  kb
transcript OTTMUST00000015865 VEGA | MGI Sequence Detail 4410 Not Applicable 
polypeptide OTTMUSP00000007286 VEGA | MGI Sequence Detail 360 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(8) UniProt(1)
Polymorphisms SNPs within 2kb(672 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002305 Aminoacyl-tRNA synthetase, class Ic
InterPro IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
InterPro IPR002306 Tryptophan-tRNA ligase
InterPro IPR024109 Tryptophan-tRNA ligase, bacterial-type
Protein Ontology PR:000017370 tryptophanyl-tRNA synthetase, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:155529 Wakasugi K, Species-specific differences in the regulation of the aminoacylation activity of mammalian tryptophanyl-tRNA synthetases. FEBS Lett. 2010 Jan 4;584(1):229-32
All references(36)
Other
accession IDs
MGI:1924510, MGI:2139688

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory