Map7d2 MGI Mouse Gene Detail - MGI:1917474

Symbol

Map7d2
Name

MAP7 domain containing 2
Synonyms

1600028E09Rik, 2900002G04Rik, 5330432J06Rik, C030036K04Rik, Mtap7d2

Feature Type

protein coding gene
IDs

MGI:1917474
NCBI Gene: 78283
Alliance

gene page
Transcription Start Sites

14 TSS

Sequence Map

ChrX:158197568-158281753 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 73.45 cM, cytoband F4
Mapping Data

2 experiments

SNPs within 2kb

1732 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917474	protein coding gene	ChrX:158197488-158281954 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0036225	protein coding gene	ChrX:157310098-157397621 (+)
A/J	MGP_AJ_G0036195	protein coding gene	ChrX:156590187-156679956 (+)
AKR/J	MGP_AKRJ_G0036123	protein coding gene	ChrX:161561065-161655085 (+)
BALB/cJ	MGP_BALBcJ_G0036188	protein coding gene	ChrX:154667121-154764128 (+)
C3H/HeJ	MGP_C3HHeJ_G0035894	protein coding gene	ChrX:157702310-157796024 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0036710	protein coding gene	ChrX:162000179-162088730 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033532	protein coding gene	ChrX:147867212-147947459 (+)
CAST/EiJ	MGP_CASTEiJ_G0035183	protein coding gene	ChrX:136743758-136836209 (+)
CBA/J	MGP_CBAJ_G0035869	protein coding gene	ChrX:166616250-166708927 (+)
DBA/2J	MGP_DBA2J_G0036035	protein coding gene	ChrX:155575312-155663110 (+)
FVB/NJ	MGP_FVBNJ_G0035966	protein coding gene	ChrX:154703102-154783590 (+)
LP/J	MGP_LPJ_G0036120	protein coding gene	ChrX:158473108-158559636 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035998	protein coding gene	ChrX:175300883-175399265 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036751	protein coding gene	ChrX:156854676-156944784 (+)
PWK/PhJ	MGP_PWKPhJ_G0034881	protein coding gene	ChrX:133624193-133709687 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034702	protein coding gene	ChrX:137170187-137258891 (+)
WSB/EiJ	MGP_WSBEiJ_G0035318	protein coding gene	ChrX:154824038-154911738 (+)

Human Ortholog

MAP7D2, MAP7 domain containing 2

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MAP7D2, MAP7 domain containing 2
Links

HGNC:25899

NCBI Gene ID: 256714

UniProt: Q96T17
Chr Location

Xp22.12; chrX:20006713-20116907 (-) GRCh38

MGI Vertebrate Homology

Map7d2 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: MAP7D2
Gene Tree

Map7d2

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
11 images
8 phenotype references

All Mutations and Alleles

6
Endonuclease-mediated

1
Gene trapped

3
Radiation induced

1
Spontaneous

1
Genomic Mutations

2 involving Map7d2
Find Mice (IMSR)

2 strains or lines available

Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.

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All GO Annotations

33
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

748
Tissues

8
cDNA Data

24
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase map7d2

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All Sequences

83
RefSeq

36
UniProt

4
CCDS

CCDS41193.1, CCDS85823.1, CCDS85824.1

Ensembl

ENSMUSG00000041020 (Evidence)
NCBI Gene

78283

			Length	Strain/Species	Flank
genomic	ENSMUSG00000041020	Ensembl Gene Model \| MGI Sequence Detail	84186	C57BL/6J	± kb
transcript	ENSMUST00000112471	Ensembl \| MGI Sequence Detail	3670	Not Applicable
polypeptide	ENSMUSP00000108090	Ensembl \| MGI Sequence Detail	781	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000030762 MAP7 domain-containing protein 2

(term hierarchy)
InterPro Domains

IPR051483 Microtubule-associated protein 7 domain-containing protein

IPR008604 Microtubule-associated protein 7 family
GlyGen

A2AG50 2 sites, 1 O-linked glycan (2 sites)

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All nucleic 26

Genomic 2

cDNA 24

Microarray probesets 4

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MGI:1920503, MGI:1924891, MGI:1925533

Summaries

All 36

Developmental Gene Expression 1

Gene Ontology 8

Phenotypes 8
Earliest

J:46359 Blair HJ, et al., Mouse mutants carrying deletions that remove the genes mutated in Coffin-Lowry syndrome and lactic acidosis. Hum Mol Genet. 1998 Mar;7(3):549-55
Latest

J:359782 Kikuchi K, et al., Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells. Life Sci Alliance. 2022 Aug;5(8):e202201390

TSS for Map7d2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr162481	ChrX:158197522-158197532 (+)	-41 bp
Tssr162482	ChrX:158197574-158197585 (+)	12 bp
Tssr162483	ChrX:158197633-158197651 (+)	74 bp
Tssr162484	ChrX:158197655-158197707 (+)	113 bp
Tssr5713	ChrX:158239407-158239420 (+)	41,846 bp
Tssr162485	ChrX:158242129-158242161 (+)	44,577 bp
Tssr162486	ChrX:158242163-158242189 (+)	44,608 bp
Tssr162487	ChrX:158242195-158242210 (+)	44,635 bp
Tssr162488	ChrX:158255836-158255850 (+)	58,275 bp
Tssr162489	ChrX:158255863-158255877 (+)	58,302 bp
Tssr162490	ChrX:158265271-158265290 (+)	67,713 bp
Tssr162491	ChrX:158265981-158265997 (+)	68,421 bp
Tssr162492	ChrX:158271808-158271811 (+)	74,242 bp
Tssr162493	ChrX:158272305-158272323 (+)	74,746 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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