About   Help   FAQ
H1fnt Gene Detail
Summary
  • Symbol
    H1fnt
  • Name
    H1 histone family, member N, testis-specific
  • Synonyms
    1700026P10Rik, H1T2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917319
    NCBI Gene: 70069
Location & Maps
more
  • Sequence Map
    Chr15:98255982-98257307 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1326 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    H1FNT, H1 histone family member N, testis specific
  • Human Ortholog
    H1FNT, H1 histone family member N, testis specific
    Orthology source: HGNC
  • Synonyms
    H1.7, H1T2
  • Links
    NCBI Gene ID: 341567
    neXtProt AC: NX_Q75WM6

  • Chr Location
    12q13.11; chr12:48328980-48330279 (+)  GRCh38.p2

  • HCOP
    human homology predictions: H1FNT
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    3 involving H1fnt
  • Incidental Mutations
Homozygous null male mice display reduced fertility with asthenozoospermia, oligozoospermia, and teratozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70069 NCBI Gene Model | MGI Sequence Detail 1326 C57BL/6J ±  kb
transcript NM_027304 RefSeq | MGI Sequence Detail 1338 C57BL/6  
polypeptide Q8CJI4 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    25 from dbSNP Build 137
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 4
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 21
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:224007 Tang MC, et al., Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice. PLoS Genet. 2015 Feb;11(2):e1004964

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory