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Rab28 Gene Detail
Summary
  • Symbol
    Rab28
  • Name
    RAB28, member RAS oncogene family
  • Synonyms
    2700023P08Rik, MGC:8039
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917285
    NCBI Gene: 100972
Location & Maps
more
  • Sequence Map
    Chr5:41624976-41708157 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      83182 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 22.58 cM, cytoband B2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RAB28, RAB28, member RAS oncogene family
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAB28, RAB28, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CORD18
  • Links
    NCBI Gene ID: 9364
    neXtProt AC: NX_P51157

  • Chr Location
    4p15.33; chr4:13296017-13484365 (-)  GRCh38.p2
Human Diseases
more
  • Diseases
    1 with human RAB28 associations

Human Disease Mouse Models
       Cone-Rod Dystrophy 18; CORD18   OMIM: 615374
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    6 involving Rab28
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    47
  • Tissues
    9
  • cDNA Data
    72
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055786 VEGA Gene Model | MGI Sequence Detail 83182 C57BL/6J ±  kb
transcript OTTMUST00000138072 VEGA | MGI Sequence Detail 1635 Not Applicable  
polypeptide OTTMUSP00000072644 VEGA | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    362 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013602 ras-related protein Rab-28
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 72
    cDNA 72

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141204
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 5
    Phenotypes 24
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory