Rab28
Gene Detail

Symbol

Name
ID

Rab28
RAB28, member RAS oncogene family
MGI:1917285

Synonyms

2700023P08Rik, MGC:8039

Feature Type

protein coding gene

Genetic Map

Chromosome 5
22.58 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr5:41624976-41708155 bp, - strand From Ensembl annotation of GRCm38   83180 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:3135  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab28

Human
homologs

Human Homolog		RAB28, RAB28, member RAS oncogene family
NCBI Gene ID		9364
neXtProt AC		NX_P51157
Human Synonyms		CORD18
Human Chr (Location)		4p15.33; chr4:13342239-13484365 (-)  GRCh38
Disease Associations		(1) Diseases Associated with Human RAB28

Mutations,
alleles, and
phenotypes

All mutations/alleles(8) : Chemically induced (ENU)(1) Gene trapped(3) Radiation induced(2) Targeted(2)
Genomic Mutations involving Rab28 (3)
Incidental mutations (data from Mutagenetix , APF )
Mutations Annotated to Human Diseases (2)    Phenotype Images(4)

Interactions

Rab28 interacts with 140 markers (Mir9-1, Mir9-2, Mir9-3, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (13 annotations)

Process	small GTPase mediated signal transduction, toxin transport
Component	cell projection, ciliary basal body, ...
Function	GDP binding, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)

Data Summary: Results (47)    Tissues (9)    Images (18)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	47

cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(72) cDNA(72)
Microarray probesets(4)

Other database
links

Ensembl Gene Model	ENSMUSG00000029128 (Evidence)
Entrez Gene	100972 (Evidence)
UniGene	41555
DFCI	TC1593428, TC1575428
DoTS	DT.110691239, DT.491618
NIA Mouse Gene Index	U026146
Consensus CDS Project	CCDS19258.1
International Mouse Knockout Project Status	Rab28

Sequences

Length	Strain/Species
genomic	ENSMUSG00000029128	Ensembl Gene Model | MGI Sequence Detail	83180	C57BL/6J
transcript	ENSMUST00000031011	Ensembl | MGI Sequence Detail	1636	Not Applicable
polypeptide	ENSMUSP00000031011	Ensembl | MGI Sequence Detail	221	Not Applicable

All sequences(37) RefSeq(10) UniProt(4)

Polymorphisms

SNPs within 2kb(363 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013602	ras-related protein Rab-28

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7
All references(41)

Other
accession IDs

MGI:2141204