Rab28 Gene Detail

Summary

• Symbol
  Rab28
• Name
  RAB28, member RAS oncogene family
• Synonyms
  2700023P08Rik, MGC:8039

• Feature Type
  protein coding gene
• IDs
  MGI:1917285
  NCBI Gene: 100972

Location & Maps

• Sequence Map
  Chr5:41624976-41708157 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    83182 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 22.58 cM, cytoband B2
• Mapping Data
  3 experiments

Homology

• Human Ortholog
  RAB28, RAB28, member RAS oncogene family

• Vertebrate Orthologs
  10

• Human Ortholog
  RAB28, RAB28, member RAS oncogene family
  Orthology source: HomoloGene, HGNC
• Synonyms
  CORD18
• Links
  HGNC:9768

  NCBI Gene ID: 9364

  neXtProt AC: NX_P51157

  UniProt: P51157

  
  
• Chr Location
  4p15.33; chr4:13293479-13484365 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 3135
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: RAB28
• Protein SuperFamily
  Ras-related protein Rab
• Gene Tree
  Rab28
  

Human Diseases

• Diseases
  1 with human RAB28 associations

				Human Disease	Mouse Models
				cone-rod dystrophy 18 IDs cone-rod dystrophy 18       DOID:0111024 OMIM:615374

Click on a disease name to see all genes associated with that disease.

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  24 phenotype references
  

• All Mutations and Alleles
  11
• Chemically induced (ENU)
  1
• Chemically induced (other)
  2
• Gene trapped
  3
• Radiation induced
  2
• Spontaneous
  1
• Targeted
  2
• Genomic Mutations
  6 involving Rab28
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  13
• GO References
  5

• External Resources
  FuncBase

Expression

• Assay Results
  47
• Tissues
  9
• cDNA Data
  72
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN rab28

Interactions

• Rab28 interacts with 140 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  13
• UniProt
  6
• CCDS
  CCDS19258.1, CCDS80271.1, CCDS80272.1
• UniGene
  41555

• VEGA
  OTTMUSG00000055786 (Evidence)
• Ensembl
  ENSMUSG00000029128 (Evidence)
• NCBI Gene
  100972

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000055786	VEGA Gene Model | MGI Sequence Detail	83182	C57BL/6J
transcript	OTTMUST00000138072	VEGA | MGI Sequence Detail	1635	Not Applicable
polypeptide	OTTMUSP00000072644	VEGA | MGI Sequence Detail	221	Not Applicable

Polymorphisms

• SNPs within 2kb
  362 from dbSNP Build 142

Protein
Information

• UniProt
  6 Sequences
• Protein Ontology
  PR:000013602 ras-related protein Rab-28
  (term hierarchy)
• InterPro Domains
  IPR027417 P-loop containing nucleoside triphosphate hydrolase
  IPR001806 Small GTPase superfamily
  IPR005225 Small GTP-binding protein domain

Molecular
Reagents

• All nucleic 72

  cDNA 72

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2141204

References

• Summaries
  All 55

  Developmental Gene Expression 4

  Diseases 1

  Gene Ontology 5

  Phenotypes 24
• Earliest
  J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
• Latest
  J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7