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Nt5dc2 Gene Detail
Summary
  • Symbol
    Nt5dc2
  • Name
    5'-nucleotidase domain containing 2
  • Synonyms
    2510015F01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917271
    NCBI Gene: 70021
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:31131053-31139124 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917271
protein coding gene Chr14:31130806-31139124 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021119
protein coding gene Chr14:24301972-24311459 (+)
A/J MGP_AJ_G0021067
protein coding gene Chr14:23385161-23392874 (+)
AKR/J MGP_AKRJ_G0021044
protein coding gene Chr14:24509074-24516842 (+)
BALB/cJ MGP_BALBcJ_G0021071
protein coding gene Chr14:23506615-23514511 (+)
C3H/HeJ MGP_C3HHeJ_G0020854
protein coding gene Chr14:24378347-24382444 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021503
protein coding gene Chr14:25274434-25281579 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019066
protein coding gene Chr14:23448081-23455992 (+)
CAST/EiJ MGP_CASTEiJ_G0020379
protein coding gene Chr14:24141093-24149624 (+)
CBA/J MGP_CBAJ_G0020821
protein coding gene Chr14:26247633-26253905 (+)
DBA/2J MGP_DBA2J_G0020943
protein coding gene Chr14:23414724-23422554 (+)
FVB/NJ MGP_FVBNJ_G0020927
protein coding gene Chr14:23380618-23384971 (+)
LP/J MGP_LPJ_G0021012
protein coding gene Chr14:24629008-24638668 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020953
protein coding gene Chr14:25513138-25518726 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021536
protein coding gene Chr14:24273288-24277506 (+)
PWK/PhJ MGP_PWKPhJ_G0020127
protein coding gene Chr14:22870430-22878132 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019951
protein coding gene Chr14:23866132-23873887 (+)
WSB/EiJ MGP_WSBEiJ_G0020434
protein coding gene Chr14:24328377-24336172 (+)



Homology
more
  • Human Ortholog
    NT5DC2, 5'-nucleotidase domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NT5DC2, 5'-nucleotidase domain containing 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 64943
    neXtProt AC: NX_Q9H857
    UniProt: Q9H857

  • Chr Location
    3p21.1; chr3:52524369-52535077 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071547 Ensembl Gene Model | MGI Sequence Detail 8072 C57BL/6J ±  kb
transcript ENSMUST00000227096 Ensembl | MGI Sequence Detail 1848 Not Applicable  
polypeptide ENSMUSP00000154475 Ensembl | MGI Sequence Detail 553 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR036412 HAD-like superfamily
    IPR023214 HAD superfamily
    IPR008380 HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase
    IPR016695 Purine 5'-nucleotidase
Molecular
Reagents
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  • All nucleic 100
    cDNA 98
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:198109 Oeschger FM, et al., Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory