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Ndufaf1 Gene Detail
Summary
  • Symbol
    Ndufaf1
  • Name
    NADH:ubiquinone oxidoreductase complex assembly factor 1
  • Synonyms
    2410001M24Rik, CGI-65, CIA30
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916952
    NCBI Gene: 69702
  • Gene Overview
    MyGene.info: NDUFAF1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119655446-119662827 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.97 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916952
protein coding gene Chr2:119655446-119662885 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026348
protein coding gene Chr2:122475414-122483604 (-)
A/J MGP_AJ_G0026309
protein coding gene Chr2:117460126-117468210 (-)
AKR/J MGP_AKRJ_G0026288
protein coding gene Chr2:120741631-120751985 (-)
BALB/cJ MGP_BALBcJ_G0026322
protein coding gene Chr2:117704270-117712327 (-)
C3H/HeJ MGP_C3HHeJ_G0026068
protein coding gene Chr2:121205312-121215524 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026769
protein coding gene Chr2:126462904-126470129 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024149
protein coding gene Chr2:112493090-112501416 (-)
CAST/EiJ MGP_CASTEiJ_G0025530
protein coding gene Chr2:121524716-121532848 (-)
CBA/J MGP_CBAJ_G0026044
protein coding gene Chr2:130904103-130913378 (-)
DBA/2J MGP_DBA2J_G0026183
protein coding gene Chr2:116860523-116868583 (-)
FVB/NJ MGP_FVBNJ_G0026145
protein coding gene Chr2:115690072-115698956 (-)
LP/J MGP_LPJ_G0026284
protein coding gene Chr2:122741427-122749747 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026164
protein coding gene Chr2:135223609-135239813 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026824
protein coding gene Chr2:120856753-120866187 (-)
PWK/PhJ MGP_PWKPhJ_G0025266
protein coding gene Chr2:116443569-116450816 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025065
protein coding gene Chr2:120049328-120058924 (-)
WSB/EiJ MGP_WSBEiJ_G0025599
protein coding gene Chr2:121689134-121702512 (-)



Homology
more
  • Human Ortholog
    NDUFAF1, NADH:ubiquinone oxidoreductase complex assembly factor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFAF1, NADH:ubiquinone oxidoreductase complex assembly factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI65, CGI-65, CIA30
  • Links
    NCBI Gene ID: 51103
    neXtProt AC: NX_Q9Y375
    UniProt: Q9Y375

  • Chr Location
    15q15.1; chr15:41387349-41402694 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NDUFAF1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027305 Ensembl Gene Model | MGI Sequence Detail 7382 C57BL/6J ±  kb
transcript ENSMUST00000028768 Ensembl | MGI Sequence Detail 1451 Not Applicable  
polypeptide ENSMUSP00000028768 Ensembl | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR039131 Complex I intermediate-associated protein 30, mitochondrial
    IPR008979 Galactose-binding-like domain superfamily
    IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Molecular
Reagents
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  • All nucleic 35
    cDNA 34
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:255082 Kurogi S, et al., Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep. 2017 Jan 20;7:40692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory