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Klk12 Gene Detail
Summary
  • Symbol
    Klk12
  • Name
    kallikrein related-peptidase 12
  • Synonyms
    2310008B01Rik, KLK-L5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916761
    NCBI Gene: 69511
  • Gene Overview
    MyGene.info: KLK12
Location & Maps
more
  • Sequence Map
    Chr7:43768897-43773585 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4689 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.26 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    KLK12, kallikrein related peptidase 12
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KLK12, kallikrein related peptidase 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KLKL5, KLK-L5
  • Links
    NCBI Gene ID: 43849
    neXtProt AC: NX_Q9UKR0

  • Chr Location
    19q13.33; chr19:51028960-51035652 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022522 VEGA Gene Model | MGI Sequence Detail 4689 C57BL/6J ±  kb
transcript OTTMUST00000053935 VEGA | MGI Sequence Detail 1115 Not Applicable  
polypeptide OTTMUSP00000025680 VEGA | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141912
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory