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Ascc1
Gene Detail
Symbol

Name
ID
Ascc1
activating signal cointegrator 1 complex subunit 1
MGI:1916340
Synonyms
1810015P09Rik, ASC1p50, CGI-18
Feature Type
protein coding gene
Genetic Map
Chromosome 10
29.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:60002805-60099990 bp, + strand
From Ensembl annotation of GRCm38

  97186 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41079  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ASCC1
Protein SuperFamily: phosphoesterase, eukaryotic LigT type
Gene Tree: Ascc1

Human
homologs
ASCC1, activating signal cointegrator 1 complex subunit 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51008
neXtProt AC: NX_Q8N9N2

Human Synonyms: ASC1p50, CGI-18, p50

Human Chr (Location): 10pter-q25.3; chr10:72096032-72217134 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ASCC1

Mutations,
alleles, and
phenotypes
All mutations/alleles(42) : Gene trapped(40) Targeted(2)
Incidental mutations (data from APF )
Interactions
Ascc1 interacts with 49 markers (Mir1a-1, Mir1a-2, Mir30c-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component cytoplasm, transcription factor complex
Function nucleic acid binding, RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (65)    Tissues (29)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 63
RT-PCR 2
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ascc1 ; ZFIN ascc1    NEW 
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000044475 (Evidence)
Entrez Gene 69090 (Evidence)
DFCI TC1578033, TC1675063, TC1615822
DoTS DT.94212820, DT.490824, DT.97412787, DT.99849793
NIA Mouse Gene Index U011553
Consensus CDS Project CCDS23870.1
International Mouse Phenotyping Consortium Status Ascc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044475 Ensembl Gene Model | MGI Sequence Detail 97186 C57BL/6J ±  kb
transcript ENSMUST00000050516 Ensembl | MGI Sequence Detail 1488 Not Applicable 
polypeptide ENSMUSP00000052351 Ensembl | MGI Sequence Detail 356 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(12) UniProt(2)
Polymorphisms
SNPs within 2kb(544 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004087 K Homology domain
InterPro IPR004088 K Homology domain, type 1
InterPro IPR009210 Predicted eukaryotic LigT
InterPro IPR019510 Protein kinase A anchor protein, nuclear localisation signal domain
InterPro IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase
Protein Ontology PR:000004359 activating signal cointegrator 1 complex subunit 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)
Other
accession IDs
MGI:2143642

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory