Ascc1
Gene Detail

Symbol Name ID

Ascc1 activating signal cointegrator 1 complex subunit 1 MGI:1916340

Synonyms

1810015P09Rik, ASC1p50, CGI-18

Feature Type

protein coding gene

Genetic Map

Chromosome 10

29.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr10:60002805-60099990 bp, + strand From NCBI annotation of GRCm38   97186 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41079  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: phosphoesterase, eukaryotic LigT type
Gene Tree: Ascc1

Human homologs

Human Homolog		ASCC1, activating signal cointegrator 1 complex subunit 1
NCBI Gene ID		51008
neXtProt AC		NX_Q8N9N2
Human Synonyms		ASC1p50, p50
Human Chr (Location)		10pter-q25.3; chr10:73855790-73976892 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ASCC1

Alleles and phenotypes

All alleles(42) : Targeted(2) Gene trapped(40)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	regulation of transcription, DNA-dependent, RNA metabolic process, ...
Component	cytoplasm, transcription factor complex
Function	catalytic activity, RNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (65)    Tissues (29)    Images (17)
Theiler Stages: 21, 23, 28

Assay Type	Results
RNA in situ	63
RT-PCR	2

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000044475 (Evidence)
Entrez Gene	69090 (Evidence)
DFCI	TC1578033, TC1615822, TC1675063
DoTS	DT.490824, DT.94212820, DT.97412787, DT.99849793
NIA Mouse Gene Index	U011553
Consensus CDS Project	CCDS23870.1
International Mouse Knockout Project Status	Ascc1

Sequences

Length	Strain/Species
genomic	69090	NCBI Gene Model | MGI Sequence Detail	97186	C57BL/6J
transcript	NM_026937	RefSeq | MGI Sequence Detail	1505	C57BL/6
polypeptide	Q9D8Z1	UniProt | EBI | MGI Sequence Detail	356	Not Applicable

All sequences(37) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(355 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004087	K Homology domain
InterPro	IPR004088	K Homology domain, type 1
InterPro	IPR009210	Predicted eukaryotic LigT
InterPro	IPR019510	Protein kinase A anchor protein, nuclear localisation signal domain
InterPro	IPR009097	RNA ligase/cyclic nucleotide phosphodiesterase
Protein Ontology	PR:000004359	activating signal cointegrator 1 complex subunit 1

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Other accession IDs

MGI:2143642