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Wdr53 Gene Detail
Summary
  • Symbol
    Wdr53
  • Name
    WD repeat domain 53
  • Synonyms
    1500002B03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916230
    NCBI Gene: 68980
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:32066047-32075901 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 22.47 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916230
 protein coding gene Chr16:32066045-32075901 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022733
 protein coding gene Chr16:30300012-30310077 (+)
A/J MGP_AJ_G0022698
 protein coding gene Chr16:28870076-28880359 (+)
AKR/J MGP_AKRJ_G0022671
 protein coding gene Chr16:29922241-29932062 (+)
BALB/cJ MGP_BALBcJ_G0022700
 protein coding gene Chr16:29021318-29031295 (+)
C3H/HeJ MGP_C3HHeJ_G0022465
 protein coding gene Chr16:30046927-30056756 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023149
 protein coding gene Chr16:30937005-30949332 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020667
 protein coding gene Chr16:29234956-29244118 (+)
CAST/EiJ MGP_CASTEiJ_G0021993
 protein coding gene Chr16:30173931-30183990 (+)
CBA/J MGP_CBAJ_G0022435
 protein coding gene Chr16:32188611-32198372 (+)
DBA/2J MGP_DBA2J_G0022568
 protein coding gene Chr16:28726063-28736122 (+)
FVB/NJ MGP_FVBNJ_G0022543
 protein coding gene Chr16:28707777-28717457 (+)
LP/J MGP_LPJ_G0022635
 protein coding gene Chr16:30076823-30087573 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022562
 protein coding gene Chr16:31642513-31653824 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023161
 protein coding gene Chr16:29899971-29910910 (+)
PWK/PhJ MGP_PWKPhJ_G0021732
 protein coding gene Chr16:29040780-29051317 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021563
 protein coding gene Chr16:29698054-29707890 (+)
WSB/EiJ MGP_WSBEiJ_G0022037
 protein coding gene Chr16:29841265-29853789 (+)



Homology
more
  • Human Ortholog
    WDR53, WD repeat domain 53
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR53, WD repeat domain 53
  • Links
    NCBI Gene ID: 348793
    neXtProt AC: NX_Q7Z5U6
    UniProt: Q7Z5U6

  • Chr Location
    3q29; chr3:196554177-196568674 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68980 NCBI Gene Model | MGI Sequence Detail 9855 C57BL/6J ±  kb
    transcript NM_001399294 RefSeq | MGI Sequence Detail 1491 C57BL/6  
    polypeptide Q9DB94 UniProt | EBI | MGI Sequence Detail 358 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 25

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2146502
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:327759 Pollak RM, et al., Metabolic effects of the schizophrenia-associated 3q29 deletion. Transl Psychiatry. 2022 Feb 17;12(1):66
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory