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Trmt1l
Gene Detail
 Symbol
Name
ID
Trmt1l
tRNA methyltransferase 1 like
MGI:1916185
Synonyms 1190005F20Rik, Trm1-like
Feature Type protein coding gene
Genetic Map
Chromosome 1
64.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:151428542-151458161 bp, + strand
From VEGA annotation of GRCm38

  29620 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12801  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Trmt1l

Human
homologs
Human Homolog TRMT1L, tRNA methyltransferase 1 homolog (S. cerevisiae)-like
NCBI Gene ID 81627
neXtProt AC  NX_Q7Z2T5
Human Synonyms  bG120K12.3, C1orf25, MST070, TRM1L
Human Chr (Location)  1q25.2; chr1:185118085-185157098 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(29) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for a gene trapped allele are viable and anatomically normal but display significantly impaired motor coordination and aberrant exploratory behavior.
 
Interactions
Trmt1l interacts with 77 markers (Mir7-1, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (78 annotations)
Process adult behavior, adult locomotory behavior, ...
Function 1-hydroxy-6-methoxypyrene methyltransferase activity, 1-hydroxypyrene methyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (192)    Tissues (97)   
Theiler Stages: 18, 19, 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
In situ reporter (knock in) 122
Northern blot 14
RT-PCR 56
cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(54) cDNA(50) Primer pair(4)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000049568 (Evidence)
Ensembl Gene ModelENSMUSG00000053286 (Evidence)
Entrez Gene98685 (Evidence)
UniGene289373
DFCITC1576699, TC1591076, TC1592432, TC1627904
DoTSDT.101145634, DT.101383376, DT.102556374, DT.40162505, DT.55282829, DT.91325943, DT.94208449
NIA Mouse Gene IndexU053171
EC2.1.1.-
Consensus CDS ProjectCCDS15361.1
International Mouse Knockout Project StatusTrmt1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049568 VEGA Gene Model | MGI Sequence Detail 29620 C57BL/6J ±  kb
transcript OTTMUST00000126327 VEGA | MGI Sequence Detail 2749 Not Applicable 
polypeptide OTTMUSP00000068333 VEGA | MGI Sequence Detail 728 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(376 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002905 tRNA (guanine(26)-N(2))-dimethyltransferase
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000016676 TRM1-like protein
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:2138580

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory