1190003J15Rik
Gene Detail

Symbol Name ID

1190003J15Rik RIKEN cDNA 1190003J15 gene MGI:1916142

Synonyms

2810420C16Rik, Urah

Feature Type

protein coding gene

Genetic Map

Chromosome 7

86.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:140835018-140837966 bp, + strand From VEGA annotation of GRCm38   2949 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:45975  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 2 zebrafish

Protein SuperFamily: transthyretin/transthyretin-related protein
Gene Tree: 1190003J15Rik

Alleles and phenotypes

All alleles(9) : Targeted(2) Gene trapped(6) Chemically induced(1)
 

Mice homozygous for an ENU mutation have an elevated platelet cell number, display hepatomegaly and hepatocellular carcinoma.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	metabolic process, purine nucleobase metabolic process, ...
Component	mitochondrion, peroxisome
Function	hydrolase activity, hydroxyisourate hydrolase activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(37)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(37) cDNA(37)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000024526 (Evidence)
Ensembl Gene Model	ENSMUSG00000025481 (Evidence)
Entrez Gene	76974 (Evidence)
UniGene	272359
DFCI	TC1582402
DoTS	DT.532352, DT.94234306
NIA Mouse Gene Index	U040692
EC	3.5.2.17
Consensus CDS Project	CCDS21986.1
International Mouse Knockout Project Status	1190003J15Rik

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024526	VEGA Gene Model | MGI Sequence Detail	2949	C57BL/6J
transcript	OTTMUST00000060193	VEGA | MGI Sequence Detail	719	Not Applicable
polypeptide	OTTMUSP00000029354	VEGA | MGI Sequence Detail	118	Not Applicable

All sequences(25) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(19 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014306	Hydroxyisourate hydrolase
InterPro	IPR023419	Transthyretin, conserved site
InterPro	IPR000895	Transthyretin/hydroxyisourate hydrolase
InterPro	IPR023416	Transthyretin/hydroxyisourate hydrolase, superfamily
Protein Ontology	PR:000017227	5-hydroxyisourate hydrolase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGI:1924224