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Mtcl1
Gene Detail
 Symbol
Name
ID
Mtcl1
microtubule crosslinking factor 1
MGI:1915867
Synonyms 1110012J17Rik, mKIAA0802, Soga2, t8219b25
Feature Type protein coding gene
Genetic Map
Chromosome 17
35.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:66336982-66449750 bp, - strand
From VEGA annotation of GRCm38

  112769 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41017  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mtcl1

Human
homologs
Human Homolog MTCL1, microtubule crosslinking factor 1
NCBI Gene ID 23255
neXtProt AC  NX_Q9Y4B5
Human Synonyms  CCDC165, KIAA0802, SOGA2
Human Chr (Location)  18p11.22; chr18:8705661-8832778 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(53) : Gene trapped(52) Targeted(1)
Incidental mutations (data from APF )
Interactions
Mtcl1 interacts with 229 markers (Mir7-2, Mir7b, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process establishment or maintenance of epithelial cell apical/basal polarity, microtubule bundle formation, ...
Component apicolateral plasma membrane, cytoplasm, ...
Function microtubule binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (324)    Tissues (95)    Images (30)
Theiler Stages: 9, 12, 13, 14, 15, 23, 26, 28
Assay TypeResults
RNA in situ 324
cDNA source data(8)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000033967 (Evidence)
Ensembl Gene ModelENSMUSG00000052105 (Evidence)
Entrez Gene68617 (Evidence)
DFCITC1576550, TC1589196, TC1628659
DoTSDT.101387605, DT.101735102, DT.102557026, DT.60117704
NIA Mouse Gene IndexU038015
Consensus CDS ProjectCCDS28946.2, CCDS50168.1
International Mouse Knockout Project StatusMtcl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033967 VEGA Gene Model | MGI Sequence Detail 112769 C57BL/6J ±  kb
transcript OTTMUST00000085703 VEGA | MGI Sequence Detail 7221 Not Applicable 
polypeptide OTTMUSP00000046328 VEGA | MGI Sequence Detail 1945 Not Applicable 

For the selected sequences
All sequences(81) RefSeq(24) UniProt(4)
Polymorphisms SNPs within 2kb(774 from dbSNP Build 137)
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206886 Sato Y, et al., The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells. J Cell Sci. 2013 Oct 15;126(Pt 20):4671-83
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory