Ube2c
Gene Detail

Symbol Name ID

Ube2c ubiquitin-conjugating enzyme E2C MGI:1915862

Synonyms

1110015A16Rik, D2Ertd695e

Feature Type

protein coding gene

Genetic Map

Chromosome 2

85.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:164769898-164778822 bp, + strand From VEGA annotation of GRCm38   8925 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5096  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ubiquitin-conjugating enzyme E2
Gene Tree: Ube2c

Human homologs

Human Homolog		UBE2C, ubiquitin-conjugating enzyme E2C
NCBI Gene ID		11065
neXtProt AC		NX_O00762
Human Synonyms		dJ447F3.2, UBCH10
Human Chr (Location)		20q13.12; chr20:44441255-44445596 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(13) : Targeted(1) Gene trapped(12)

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, ...
Component	anaphase-promoting complex
Function	acid-amino acid ligase activity, ATP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22

Assay Type	Results
RNA in situ	1

cDNA source data(72)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(73) cDNA(72) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000001153 (Evidence)
Ensembl Gene Model	ENSMUSG00000001403 (Evidence)
Entrez Gene	68612 (Evidence)
UniGene	89830
DFCI	TC1576329
DoTS	DT.103599940, DT.97360384
NIA Mouse Gene Index	U002816
EC	6.3.2.19
Consensus CDS Project	CCDS17055.1
International Mouse Knockout Project Status	Ube2c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000001153	VEGA Gene Model | MGI Sequence Detail	8925	C57BL/6J
transcript	OTTMUST00000002246	VEGA | MGI Sequence Detail	967	Not Applicable
polypeptide	OTTMUSP00000001095	VEGA | MGI Sequence Detail	179	Not Applicable

All sequences(31) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(20 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023313	Ubiquitin-conjugating enzyme, active site
InterPro	IPR000608	Ubiquitin-conjugating enzyme, E2
InterPro	IPR016135	Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology	PR:000016967	ubiquitin-conjugating enzyme E2 C

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Other accession IDs

MGI:1277160