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Qars
Gene Detail
Symbol

Name
ID
Qars
glutaminyl-tRNA synthetase
MGI:1915851
Synonyms
1110018N24Rik, 1200016L19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.44 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:108508005-108515941 bp, + strand
From VEGA annotation of GRCm38

  7937 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133975  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Qars

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Qars interacts with 160 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process negative regulation of apoptotic process, translation
Component aminoacyl-tRNA synthetase multienzyme complex
Function aminoacyl-tRNA ligase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(283)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(284) cDNA(283) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000034113 (Evidence)
Ensembl Gene ModelENSMUSG00000032604 (Evidence)
Entrez Gene97541 (Evidence)
UniGene272427
DFCITC1574011, TC1594416, TC1641049, TC1685371, TC1732724, TC1778207
DoTSDT.101238152, DT.101366342, DT.101389618, DT.101389625, DT.110621618, DT.535848, DT.91398682, DT.97332304, DT.97397526, DT.97400085, DT.99867652
NIA Mouse Gene IndexU011028
Consensus CDS ProjectCCDS23530.1, CCDS52926.1
International Mouse Knockout Project StatusQars
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034113 VEGA Gene Model | MGI Sequence Detail 7937 C57BL/6J ±  kb
transcript OTTMUST00000086264 VEGA | MGI Sequence Detail 2501 Not Applicable 
polypeptide OTTMUSP00000046692 VEGA | MGI Sequence Detail 775 Not Applicable 

For the selected sequences
All sequences(100) RefSeq(4) UniProt(14)
Polymorphisms
SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site
InterPro IPR004514 Glutamine-tRNA synthetase, class Ib
InterPro IPR007638 Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2
InterPro IPR007639 Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal
InterPro IPR000924 Glutamyl/glutaminyl-tRNA synthetase, class Ib
InterPro IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain
InterPro IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
InterPro IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
InterPro IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain
InterPro IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000013561 glutaminyl-tRNA synthetase
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:1918980, MGI:2143413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory