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Qars
Gene Detail
Symbol

Name
ID
Qars
glutaminyl-tRNA synthetase
MGI:1915851
Synonyms
1110018N24Rik, 1200016L19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.44 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:108507713-108515941 bp, + strand
From VEGA annotation of GRCm38

  8229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133975  Vertebrate Homology Class
1 mouse; 1 rat

HCOP human homology predictions: QARS
Gene Tree: Qars

Human
homologs
QARS, glutaminyl-tRNA synthetase
Orthology source: HGNC

IDs:
NCBI Gene ID: 5859
neXtProt AC: NX_P47897

Human Synonyms: GLNRS, MSCCA, PRO2195

Human Chr (Location): 3p21.31; chr3:49095932-49105129 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human QARS

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Qars interacts with 159 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of apoptotic process
Component aminoacyl-tRNA synthetase multienzyme complex
Function glutamine-tRNA ligase activity, protein kinase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(283)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase qars ; ZFIN qars    NEW 
Molecular
reagents
All nucleic(284) cDNA(283) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000034113 (Evidence)
Ensembl Gene Model ENSMUSG00000032604 (Evidence)
Entrez Gene 97541 (Evidence)
UniGene 272427
DFCI TC1574011, TC1594416, TC1641049, TC1685371, TC1732724, TC1778207
DoTS DT.101238152, DT.101366342, DT.101389618, DT.101389625, DT.110621618, DT.535848, DT.91398682, DT.97332304, DT.97397526, DT.97400085, DT.99867652
NIA Mouse Gene Index U011028
Consensus CDS Project CCDS23530.1, CCDS52926.1
International Mouse Phenotyping Consortium Status Qars
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034113 VEGA Gene Model | MGI Sequence Detail 8229 C57BL/6J ±  kb
transcript OTTMUST00000086264 VEGA | MGI Sequence Detail 2793 Not Applicable 
polypeptide OTTMUSP00000046692 VEGA | MGI Sequence Detail 775 Not Applicable 

For the selected sequences
All sequences(109) RefSeq(4) UniProt(9)
Polymorphisms
SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site
InterPro IPR004514 Glutamine-tRNA synthetase
InterPro IPR007638 Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2
InterPro IPR007639 Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal
InterPro IPR000924 Glutamyl/glutaminyl-tRNA synthetase
InterPro IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain
InterPro IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
InterPro IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
InterPro IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain
InterPro IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000013561 glutaminyl-tRNA synthetase
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:1918980, MGI:2143413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory