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Mocos
Gene Detail
 Symbol
Name
ID
Mocos
molybdenum cofactor sulfurase
MGI:1915841
Synonyms 1110018O12Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
13.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr18:24653691-24701556 bp, + strand
From NCBI annotation of GRCm38

  47866 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9931  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mocos

Human
homologs
Human Homolog MOCOS, molybdenum cofactor sulfurase
NCBI Gene ID 55034
neXtProt AC  NX_Q96EN8
Human Synonyms  HMCS, MCS, MOS
Human Chr (Location)  18q12; chr18:36187517-36268722 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(10) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mocos interacts with 38 markers (Mir30c-1, Mir30c-2, Mir139, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process metabolic process, molybdopterin cofactor metabolic process, ...
Component cellular_component
Function catalytic activity, molybdenum ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (9)    Tissues (2)    Images (8)
Theiler Stages: 23
Assay TypeResults
RNA in situ 9
cDNA source data(34)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000039616 (Evidence)
Entrez Gene68591 (Evidence)
UniGene28252
DFCITC1601925, TC1606108
DoTSDT.101720834, DT.529912
NIA Mouse Gene IndexU018485
EC2.8.1.9
Consensus CDS ProjectCCDS37750.1
International Mouse Knockout Project StatusMocos
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68591 NCBI Gene Model | MGI Sequence Detail 47866 C57BL/6J ±  kb
transcript NM_026779 RefSeq | MGI Sequence Detail 2884 Not Specified 
polypeptide Q14CH1 UniProt | EBI | MGI Sequence Detail 862 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(200 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000192 Aminotransferase, class V/Cysteine desulfurase
InterPro IPR005302 Molybdenum cofactor sulfurase, C-terminal
InterPro IPR005303 MOSC, N-terminal beta barrel
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
InterPro IPR011037 Pyruvate kinase-like, insert domain
Protein Ontology PR:000010511 molybdenum cofactor sulfurase
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory