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Ift80
Gene Detail
 Symbol
Name
ID
Ift80
intraflagellar transport 80
MGI:1915509
Synonyms 4921524P20Rik, Wdr56
Feature Type protein coding gene
Genetic Map
Chromosome 3
32.07 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:68892499-69004559 bp, - strand
From VEGA annotation of GRCm38

  112061 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12253  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ift80

Human
homologs
Human Homolog IFT80, intraflagellar transport 80 homolog (Chlamydomonas)
NCBI Gene ID 57560
neXtProt AC  NX_Q9P2H3
Human Synonyms  ATD2, SRTD2, WDR56
Human Chr (Location)  3q25.33; chr3:160256986-160399532 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human IFT80
Alleles
and
phenotypes
All alleles(27) : Targeted(4) Gene trapped(23)
 
Mice homozygous for a hypomorphic gene trap allele exhibit partial perinatal lethality, decreased body size, postnatal growth retardation, shortened long bones, constricted thoracic cage, periaxial polydactyly, and small cranium.
 
Human Diseases Modeled Using Mouse Ift80 (2)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process bone morphogenesis, chondrocyte differentiation, ...
Component cell, cell projection, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (47)    Tissues (10)    Images (21)
Theiler Stages: 11, 18, 23
Assay TypeResults
RNA in situ 42
In situ reporter (knock in) 5
cDNA source data(65)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(65) cDNA(65)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000024494 (Evidence)
Ensembl Gene ModelENSMUSG00000027778 (Evidence)
Entrez Gene68259 (Evidence)
UniGene389451
DFCITC1576385, TC1661061
DoTSDT.103573278, DT.55279660, DT.60117976, DT.91348027, DT.94228610
NIA Mouse Gene IndexU024136
Consensus CDS ProjectCCDS38451.1
International Mouse Knockout Project StatusIft80
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024494 VEGA Gene Model | MGI Sequence Detail 112061 C57BL/6J ±  kb
transcript OTTMUST00000060100 VEGA | MGI Sequence Detail 4063 Not Applicable 
polypeptide OTTMUSP00000029301 VEGA | MGI Sequence Detail 777 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(387 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000008938 intraflagellar transport protein 80
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203626 Howard PW, et al., Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17. Exp Cell Res. 2013 Aug 15;319(14):2275-81
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory