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N6amt2
Gene Detail
Symbol

Name
ID
N6amt2
N-6 adenine-specific DNA methyltransferase 2 (putative)
MGI:1915293
Synonyms
2510005D08Rik, Ayu21-96, GtAyu21-96, Gt(Ayu21)96Imeg
Feature Type
protein coding gene
Genetic Map
Chromosome 14
30.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:57549598-57571569 bp, - strand
From Ensembl annotation of GRCm38

  21972 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5952  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: N6AMT2
Gene Tree: N6amt2

Human
homologs
N6AMT2, N-6 adenine-specific DNA methyltransferase 2 (putative)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 221143
neXtProt AC: NX_Q8WVE0

Human Synonyms: ESP13

Human Chr (Location): 13q12.11; chr13:20728931-20773956 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(36) : Gene trapped(34) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
N6amt2 interacts with 17 markers (Mir22, Mir146, Mir146b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (71 annotations)
Process methylation
Component cytoplasm, extracellular exosome
Function 1-hydroxy-6-methoxypyrene methyltransferase activity, 1-hydroxypyrene methyltransferase activity, ...
External Resources: FuncBase
Expression
cDNA source data(52)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase n6amt2 ; ZFIN n6amt2    NEW 
Molecular
reagents
All nucleic(52) cDNA(52)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000021951 (Evidence)
Entrez Gene 68043 (Evidence)
UniGene 45225
DFCI TC1578583
DoTS DT.534552
NIA Mouse Gene Index U035626
EC 2.1.1.-
Consensus CDS Project CCDS27157.1
International Mouse Phenotyping Consortium Status N6amt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021951 Ensembl Gene Model | MGI Sequence Detail 21972 C57BL/6J ±  kb
transcript ENSMUST00000022518 Ensembl | MGI Sequence Detail 836 Not Applicable 
polypeptide ENSMUSP00000022518 Ensembl | MGI Sequence Detail 224 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(145 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002052 DNA methylase, N-6 adenine-specific, conserved site
InterPro IPR019369 DNA methylase, N-6 adenine-specific, eukaryotic
Protein Ontology PR:000010943 N(6)-adenine-specific DNA methyltransferase 2
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2145784, MGI:3629757

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory