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Anp32b
Gene Detail
Symbol

Name
ID
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
MGI:1914878
Synonyms
2410015B15Rik, PAL31, PHAPI2a
Feature Type
protein coding gene
Genetic Map
Chromosome 4
24.79 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:46450902-46472657 bp, + strand
From VEGA annotation of GRCm38

  21756 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137872  Vertebrate Homology Class
1 mouse; 1 rat

HCOP human homology predictions: ANP32B
Gene Tree: Anp32b

Human
homologs
ANP32B, acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
Orthology source: HGNC

IDs:
NCBI Gene ID: 10541
neXtProt AC: NX_Q92688

Human Synonyms: APRIL, PHAPI2, SSP29

Human Chr (Location): 9q22.32; chr9:97983207-98015943 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(271) : Gene trapped(268) Targeted(3)
Incidental mutations (data from Mutagenetix )
 
Mice homozygous for a knock-out allele exhibit partial perinatal lethality associated with failure to initiate breathing, craniofacial defects, enlarged brain ventricle, expanded inner ear cavities, plaate closure defects, decreased body size and weight, premature aging, and premature death.
 
Interactions
Anp32b interacts with 101 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process G1/S transition of mitotic cell cycle, inner ear development, ...
Component nucleus
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (32)    Tissues (32)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 28
RT-PCR 4
cDNA source data(168)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase anp32b ; ZFIN anp32b    NEW 
Molecular
reagents
All nucleic(170) cDNA(169) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006891 (Evidence)
Ensembl Gene Model ENSMUSG00000028333 (Evidence)
Entrez Gene 67628 (Evidence)
UniGene 263913
DFCI TC1574056, TC1637479, TC1680580
DoTS DT.494704, DT.110839704, DT.101157540
NIA Mouse Gene Index U004288, U094945
Consensus CDS Project CCDS18151.1
International Mouse Phenotyping Consortium Status Anp32b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006891 VEGA Gene Model | MGI Sequence Detail 21756 C57BL/6J ±  kb
transcript OTTMUST00000015913 VEGA | MGI Sequence Detail 1716 Not Applicable 
polypeptide OTTMUSP00000007314 VEGA | MGI Sequence Detail 272 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(124 from dbSNP Build 137)    SNPs within 2kb including multiple locations(130)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
InterPro IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
Protein Ontology PR:000004066 acidic leucine-rich nuclear phosphoprotein 32 family member B
References
(Earliest) J:64959 Misawa K, et al., A method to identify cDNAs based on localization of green fluorescent protein fusion products. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3062-6
(Latest) J:217538 Lui JH, et al., Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. Nature. 2014 Nov 13;515(7526):264-8
All references(39)
Other
accession IDs
MGI:1926203

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory