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Ndufa10
Gene Detail
Symbol

Name
ID
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
MGI:1914523
Synonyms
2900053E13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
46.40 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:92439010-92473860 bp, - strand
From VEGA annotation of GRCm38

  34851 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15342  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFA10
Protein SuperFamily: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 10
Gene Tree: Ndufa10

Human
homologs
NDUFA10, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4705
neXtProt AC: NX_O95299

Human Synonyms: CI-42k, CI-42KD

Human Chr (Location): 2q37.3; chr2:239957372-240025402 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFA10

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ndufa10 interacts with 96 markers (Mir7-1, Mir7-2, Mir22, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (97)    Tissues (97)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 3
cDNA source data(188)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufa10 ; ZFIN ndufa10    NEW 
Molecular
reagents
All nucleic(190) cDNA(188) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000021762 (Evidence)
Ensembl Gene Model ENSMUSG00000026260 (Evidence)
Entrez Gene 67273 (Evidence)
UniGene 248778
DFCI TC1607811, TC1572902
DoTS DT.495433
NIA Mouse Gene Index U021596
Consensus CDS Project CCDS15167.1
International Mouse Phenotyping Consortium Status Ndufa10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021762 VEGA Gene Model | MGI Sequence Detail 34851 C57BL/6J ±  kb
transcript OTTMUST00000051651 VEGA | MGI Sequence Detail 2020 Not Applicable 
polypeptide OTTMUSP00000024348 VEGA | MGI Sequence Detail 355 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(256 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002624 Deoxynucleoside kinase
InterPro IPR015828 NADH:ubiquinone oxidoreductase, 42kDa subunit
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000011068 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:209583 Morais VA, et al., PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling. Science. 2014 Apr 11;344(6180):203-7
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory