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Ndufa10 Gene Detail
Summary
  • Symbol
    Ndufa10
  • Name
    NADH:ubiquinone oxidoreductase subunit A10
  • Synonyms
    2900053E13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914523
    NCBI Gene: 67273
  • Gene Overview
    MyGene.info: NDUFA10
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:92439708-92473758 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 46.40 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914523
protein coding gene Chr1:92439010-92473860 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016315
protein coding gene Chr1:94019664-94055172 (-)
A/J MGP_AJ_G0016296
protein coding gene Chr1:90648313-90683241 (-)
AKR/J MGP_AKRJ_G0016257
protein coding gene Chr1:93334063-93368913 (-)
BALB/cJ MGP_BALBcJ_G0016252
protein coding gene Chr1:90823847-90858691 (-)
C3H/HeJ MGP_C3HHeJ_G0016081
protein coding gene Chr1:93539693-93575115 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016711
protein coding gene Chr1:97582045-97616816 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014429
protein coding gene Chr1:84882024-84917310 (-)
CAST/EiJ MGP_CASTEiJ_G0015666
protein coding gene Chr1:92882131-92917156 (-)
CBA/J MGP_CBAJ_G0016057
protein coding gene Chr1:100730328-100768054 (-)
DBA/2J MGP_DBA2J_G0016160
protein coding gene Chr1:89850606-89885351 (-)
FVB/NJ MGP_FVBNJ_G0016159
protein coding gene Chr1:88906618-88941769 (-)
LP/J MGP_LPJ_G0016231
protein coding gene Chr1:95201133-95235955 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016184
protein coding gene Chr1:103917856-103952660 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016751
protein coding gene Chr1:93348122-93383828 (-)
PWK/PhJ MGP_PWKPhJ_G0015450
protein coding gene Chr1:89281711-89316569 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015233
protein coding gene Chr1:92294541-92330525 (-)
WSB/EiJ MGP_WSBEiJ_G0015724
protein coding gene Chr1:93157415-93192177 (-)



Homology
more
  • Human Ortholog
    NDUFA10, NADH:ubiquinone oxidoreductase subunit A10
  • Vertebrate Orthologs
    11
  • Human Ortholog
    NDUFA10, NADH:ubiquinone oxidoreductase subunit A10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CI-42k, CI-42KD
  • Links
    NCBI Gene ID: 4705
    neXtProt AC: NX_O95299
    UniProt: O95299

  • Chr Location
    2q37.3; chr2:239892450-240025402 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NDUFA10 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67273 NCBI Gene Model | MGI Sequence Detail 34051 C57BL/6J ±  kb
transcript NM_024197 RefSeq | MGI Sequence Detail 1222 FVB/N  
polypeptide Q99LC3 UniProt | EBI | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000011068 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
  • PDB
  • InterPro Domains
    IPR031314 Deoxynucleoside kinase domain
    IPR015828 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 191
    cDNA 189
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:209583 Morais VA, et al., PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling. Science. 2014 Apr 11;344(6180):203-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory