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Appbp2 Gene Detail
Summary
  • Symbol
    Appbp2
  • Name
    amyloid beta precursor protein (cytoplasmic tail) binding protein 2
  • Synonyms
    1300003O07Rik, mKIAA0228, PAT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914134
    NCBI Gene: 66884
  • Gene Overview
    MyGene.info: APPBP2
Location & Maps
more
  • Sequence Map
    Chr11:85187262-85235130 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      47869 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 51.34 cM, cytoband B5
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    APPBP2, amyloid beta precursor protein binding protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    APPBP2, amyloid beta precursor protein binding protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    APP-BP2, HS.84084, PAT1
  • Links
    NCBI Gene ID: 10513
    neXtProt AC: NX_Q92624

  • Chr Location
    17q23.2; chr17:60443149-60526240 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Gene trapped
    16
  • Targeted
    2
  • Genomic Mutations
    2 involving Appbp2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001027 VEGA Gene Model | MGI Sequence Detail 47869 C57BL/6J ±  kb
transcript OTTMUST00000002056 VEGA | MGI Sequence Detail 6463 Not Applicable  
polypeptide OTTMUSP00000000994 VEGA | MGI Sequence Detail 585 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    239 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004169 amyloid protein-binding protein 2
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
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  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144187
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory