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Tsfm
Gene Detail
Symbol

Name
ID
Tsfm
Ts translation elongation factor, mitochondrial
MGI:1913649
Synonyms
2310050B20Rik, 9430024O13Rik, EF-TS, EF-Tsmt
Feature Type
protein coding gene
Genetic Map
Chromosome 10
74.50 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:127011572-127030840 bp, - strand
From VEGA annotation of GRCm38

  19269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4184  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TSFM
Gene Tree: Tsfm

Human
homologs
TSFM, Ts translation elongation factor, mitochondrial
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10102
neXtProt AC: NX_P43897

Human Synonyms: EFTS, EFTSMT

Human Chr (Location): 12q14.1; chr12:57782745-57802856 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TSFM

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tsfm interacts with 101 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process mitochondrial translational elongation, translation, ...
Component intracellular, mitochondrial matrix, ...
Function poly(A) RNA binding, translation elongation factor activity
External Resources: FuncBase
Expression
cDNA source data(46)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tsfm    NEW 
Molecular
reagents
All nucleic(46) cDNA(46)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000030579 (Evidence)
Ensembl Gene Model ENSMUSG00000040521 (Evidence)
Entrez Gene 66399 (Evidence)
UniGene 29900
DFCI TC1727396, TC1595692, TC1577790
DoTS DT.532879, DT.110608790, DT.101378725
NIA Mouse Gene Index U032319
Consensus CDS Project CCDS24222.1
International Mouse Phenotyping Consortium Status Tsfm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030579 VEGA Gene Model | MGI Sequence Detail 19269 C57BL/6J ±  kb
transcript OTTMUST00000075721 VEGA | MGI Sequence Detail 1206 Not Applicable 
polypeptide OTTMUSP00000039756 VEGA | MGI Sequence Detail 324 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(218 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001816 Translation elongation factor EFTs/EF1B
InterPro IPR014039 Translation elongation factor EFTs/EF1B, dimerisation
InterPro IPR018101 Translation elongation factor Ts, conserved site
InterPro IPR009060 UBA-like
InterPro IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal
Protein Ontology PR:000016718 elongation factor Ts, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:1924571

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory