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Tsfm
Gene Detail
 Symbol
Name
ID
Tsfm
Ts translation elongation factor, mitochondrial
MGI:1913649
Synonyms 2310050B20Rik, 9430024O13Rik, EF-TS, EF-Tsmt
Feature Type protein coding gene
Genetic Map
Chromosome 10
74.50 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:127011572-127030840 bp, - strand
From VEGA annotation of GRCm38

  19269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4184  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 western clawed frog; 1 zebrafish

Gene Tree: Tsfm

Human
homologs
Human Homolog TSFM, Ts translation elongation factor, mitochondrial
NCBI Gene ID 10102
neXtProt AC  NX_P43897
Human Synonyms  EFTS, EFTSMT
Human Chr (Location)  12q14.1; chr12:57782745-57802856 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TSFM
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tsfm interacts with 101 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process translation, translational elongation
Component intracellular, mitochondrion, ...
Function poly(A) RNA binding, translation elongation factor activity
External Resources: FuncBase
Expression
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(46) cDNA(46)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000030579 (Evidence)
Ensembl Gene ModelENSMUSG00000040521 (Evidence)
Entrez Gene66399 (Evidence)
UniGene29900
DFCITC1577790, TC1595692, TC1727396
DoTSDT.101378725, DT.110608790, DT.532879
NIA Mouse Gene IndexU032319
Consensus CDS ProjectCCDS24222.1
International Mouse Knockout Project StatusTsfm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030579 VEGA Gene Model | MGI Sequence Detail 19269 C57BL/6J ±  kb
transcript OTTMUST00000075721 VEGA | MGI Sequence Detail 1206 Not Applicable 
polypeptide OTTMUSP00000039756 VEGA | MGI Sequence Detail 324 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2) UniProt(7)
Polymorphisms SNPs within 2kb(218 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001816 Translation elongation factor EFTs/EF1B
InterPro IPR014039 Translation elongation factor EFTs/EF1B, dimerisation
InterPro IPR018101 Translation elongation factor Ts, conserved site
InterPro IPR009060 UBA-like
InterPro IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal
Protein Ontology PR:000016718 elongation factor Ts, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:1924571

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory