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Wfdc21
Gene Detail
Symbol

Name
ID
Wfdc21
WAP four-disulfide core domain 21
MGI:1913357
Synonyms
1100001G20Rik, Wdnm1-like
Feature Type
protein coding gene
Genetic Map
Chromosome 11
51.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:83746940-83752642 bp, + strand
From VEGA annotation of GRCm38

  5703 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:138469  Vertebrate Homology Class
1 mouse; 1 cattle

HCOP human homology predictions: WFDC21P
Gene Tree: Wfdc21

Human
homologs
WFDC21P, WAP four-disulfide core domain 21, pseudogene
Orthology source: HGNC

IDs:
NCBI Gene ID: 645638

Human Synonyms: linc-DC, lnc-DC, LNCDC

Human Chr (Location): 17q23.1; chr17:60083566-60088467 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Wfdc21 (1)
Interactions
Wfdc21 interacts with 11 markers (Mir136, Mir186, Mir216a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process positive regulation of catalytic activity, response to lipopolysaccharide, ...
Component extracellular space
Function metalloenzyme activator activity
External Resources: FuncBase
Expression
cDNA source data(65)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) cDNA(65)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000000976 (Evidence)
Ensembl Gene Model ENSMUSG00000051748 (Evidence)
Entrez Gene 66107 (Evidence)
UniGene 902
DFCI TC1578510
DoTS DT.101206855, DT.488447
Consensus CDS Project CCDS36258.1
International Mouse Phenotyping Consortium Status Wfdc21
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000976 VEGA Gene Model | MGI Sequence Detail 5703 C57BL/6J ±  kb
transcript OTTMUST00000001916 VEGA | MGI Sequence Detail 434 Not Applicable 
polypeptide OTTMUSP00000000928 VEGA | MGI Sequence Detail 63 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(124 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory