About   Help   FAQ
Nfu1 Gene Detail
Summary
  • Symbol
    Nfu1
  • Name
    NFU1 iron-sulfur cluster scaffold
  • Synonyms
    0610006G17Rik, CGI-33, Hirip5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913290
    NCBI Gene: 56748
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:87009291-87028461 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.76 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913290
protein coding gene Chr6:87009236-87028461 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030985
protein coding gene Chr6:88345160-88365376 (+)
A/J MGP_AJ_G0030951
protein coding gene Chr6:84921889-84944477 (+)
AKR/J MGP_AKRJ_G0030882
protein coding gene Chr6:87388963-87410444 (+)
BALB/cJ MGP_BALBcJ_G0030964
protein coding gene Chr6:84932537-84955021 (+)
C3H/HeJ MGP_C3HHeJ_G0030746
protein coding gene Chr6:97069379-97088647 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031421
protein coding gene Chr6:90727274-90748391 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028605
protein coding gene Chr6:83104868-83124400 (+)
CAST/EiJ MGP_CASTEiJ_G0030073
protein coding gene Chr6:87452492-87473484 (+)
CBA/J MGP_CBAJ_G0030648
protein coding gene Chr6:94286715-94306046 (+)
DBA/2J MGP_DBA2J_G0030804
protein coding gene Chr6:84237908-84257106 (+)
FVB/NJ MGP_FVBNJ_G0030757
protein coding gene Chr6:83419451-83438916 (+)
LP/J MGP_LPJ_G0030881
protein coding gene Chr6:88364057-88384364 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030790
protein coding gene Chr6:98389441-98411701 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031448
protein coding gene Chr6:87223899-87244389 (+)
PWK/PhJ MGP_PWKPhJ_G0029788
protein coding gene Chr6:83195431-83214478 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029616
protein coding gene Chr6:86055289-86074335 (+)
WSB/EiJ MGP_WSBEiJ_G0030154
protein coding gene Chr6:87688825-87709620 (+)



Homology
more
  • Human Ortholog
    NFU1, NFU1 iron-sulfur cluster scaffold
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NFU1, NFU1 iron-sulfur cluster scaffold
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-33, HIRIP, HIRIP5, MMDS1, Nfu, NifU, NIFUC
  • Links
    NCBI Gene ID: 27247
    neXtProt AC: NX_Q9UMS0
    UniProt: Q9UMS0

  • Chr Location
    2p13.3; chr2:69396113-69438123 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NFU1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56748 NCBI Gene Model | MGI Sequence Detail 19171 C57BL/6J ±  kb
transcript NM_001170591 RefSeq | MGI Sequence Detail 968 C57BL/6  
polypeptide Q9QZ23 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 80
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory