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Nfu1
Gene Detail
 Symbol
Name
ID
Nfu1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
MGI:1913290
Synonyms 0610006G17Rik, CGI-33, Hirip5
Feature Type protein coding gene
Genetic Map
Chromosome 6
37.76 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:87009236-87028461 bp, + strand
From VEGA annotation of GRCm38

  19226 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6369  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: HIRA-interacting protein 5
Gene Tree: Nfu1

Human
homologs
Human Homolog NFU1, NFU1 iron-sulfur cluster scaffold
NCBI Gene ID 27247
neXtProt AC  NX_Q9UMS0
Human Synonyms  HIRIP, HIRIP5, MMDS1, Nfu, NifU, NIFUC
Human Chr (Location)  2p15-p13; chr2:69396113-69438071 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human NFU1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(5) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Nfu1 interacts with 23 markers (Mir29b-2, Mir103-1, Mir103-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process iron-sulfur cluster assembly
Component cytoplasm, cytosol, ...
Function 4 iron, 4 sulfur cluster binding, iron ion binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (54)    Tissues (20)   
Theiler Stages: 2, 3, 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 6
Northern blot 12
RT-PCR 36
cDNA source data(78)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(80) cDNA(79) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000029692 (Evidence)
Ensembl Gene ModelENSMUSG00000029993 (Evidence)
Entrez Gene56748 (Evidence)
UniGene23809
DFCITC1576090
DoTSDT.110795571, DT.111129209, DT.493762, DT.97382996
NIA Mouse Gene IndexU007126, U052644
PDB1VEH
Consensus CDS ProjectCCDS51836.1
International Mouse Knockout Project StatusNfu1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029692 VEGA Gene Model | MGI Sequence Detail 19226 C57BL/6J ±  kb
transcript OTTMUST00000073669 VEGA | MGI Sequence Detail 1195 Not Applicable 
polypeptide OTTMUSP00000038172 VEGA | MGI Sequence Detail 200 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(193 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017065 HIRA-interacting protein 5
InterPro IPR001075 NIF system FeS cluster assembly, NifU, C-terminal
InterPro IPR014824 NIF system FeS cluster assembly, NifU-like scaffold, N-terminal
Protein Ontology PR:000011185 NFU1 iron-sulfur cluster scaffold, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory