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Cep41
Gene Detail
 Symbol
Name
ID
Cep41
centrosomal protein 41
MGI:1891414
Synonyms 1700017E11Rik, 2810431D15Rik, Cep41, Tsga14
Feature Type protein coding gene
Genetic Map
Chromosome 6
12.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:30653457-30693749 bp, - strand
From VEGA annotation of GRCm38

  40293 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10284  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cep41

Human
homologs
Human Homolog CEP41, centrosomal protein 41kDa
NCBI Gene ID 95681
neXtProt AC  NX_Q9BYV8
Human Synonyms  JBTS15, TSGA14
Human Chr (Location)  7q32; chr7:130393771-130441210 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human CEP41
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous disruption of this gene causes an abnormal gait, increased thermal nociceptive threshold, and alterations in fertility/fecundity and eye morphology. Some embryos homozygous for a gene trapped allele die at E10-E12 exhibiting turning failure, dilated pericardial sacs, and brain anomalies.
 
Interactions
Cep41 interacts with 361 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell projection organization, cilium assembly, ...
Component cell projection, centriole, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (1)    Images (22)
Theiler Stages: 23
Assay TypeResults
RNA in situ 22
cDNA source data(42)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) cDNA(42)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000014400 (Evidence)
Ensembl Gene ModelENSMUSG00000029790 (Evidence)
Entrez Gene83922 (Evidence)
UniGene65389
DFCITC1579231, TC1594009
DoTSDT.101153487, DT.101377214, DT.530494, DT.55116010, DT.91328618
NIA Mouse Gene IndexU027123
Consensus CDS ProjectCCDS19978.1
International Mouse Knockout Project StatusCep41
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014400 VEGA Gene Model | MGI Sequence Detail 40293 C57BL/6J ±  kb
transcript OTTMUST00000034104 VEGA | MGI Sequence Detail 3447 Not Applicable 
polypeptide OTTMUSP00000015289 VEGA | MGI Sequence Detail 373 Not Applicable 

For the selected sequences
All sequences(84) RefSeq(16) UniProt(7)
Polymorphisms SNPs within 2kb(164 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001763 Rhodanese-like domain
Protein Ontology PR:000016723 centrosomal protein of 41 kDa
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:182289 Ishikawa H, et al., Proteomic analysis of mammalian primary cilia. Curr Biol. 2012 Mar 6;22(5):414-9
All references(40)
Other
accession IDs
MGI:1889830, MGI:1916627, MGI:1925624, MGI:2141435

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory