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Snord116
Complex/Cluster/Region Detail
 Symbol
Name
ID
Cluster members
Snord116
small nucleolar RNA, C/D box 116 cluster
MGI:1891407
Snord116l2, Snord116l1, Snord116l3 ... (8 members)
Synonyms MBII-85, Pwcr1
Feature Type complex/cluster/region
Genetic Map
Chromosome 7
Syntenic

Mapping data(3)
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
 
The Snord116 gene cluster is imprinted and only expressed from the paternal allele. Deletions of the Snord116 cluster may be useful in studying the role of Snord116 in growth and feeding regulation, mechanisms of obesity, and pathophysiology of Prader-Willi syndrome (PWS).
 
Human Diseases Modeled Using Mouse Snord116 (1)    Alleles Annotated to Human Diseases(2)   
Expression
Literature Summary: (7 records)
Data Summary: Results (22)    Tissues (13)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
Northern blot 18
RT-PCR 4
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(3) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
UniGene423722
NIA Mouse Gene IndexU303623, U350186, U354712, U356230, U356770, U358554, U359202, U359783
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic AC026683 GenBank | EMBL | DDBJ | MGI Sequence Detail 179493 C57BL/6J ±  kb
transcript AF241256 GenBank | EMBL | DDBJ | MGI Sequence Detail 2518 Not Specified 

For the selected sequences
All sequences(11)
References (Earliest) J:65556 de Los Santos T, et al., Small evolutionarily conserved RNA, resembling C/D box small nucleolar RNA, is transcribed from PWCR1, a novel imprinted gene in the prader-willi deletion region, which Is highly expressed in brain. Am J Hum Genet. 2000 Nov;67(5):1067-82
(Latest) J:202149 Powell WT, et al., A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure. Hum Mol Genet. 2013 Nov 1;22(21):4318-28
All references(20)
Disease annotation references (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory