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Dusp12 Gene Detail
Summary
  • Symbol
    Dusp12
  • Name
    dual specificity phosphatase 12
  • Synonyms
    1190004O14Rik, ESTM36, LMW-DSP4, mVH1, T-DSP4, VH1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890614
    NCBI Gene: 80915
  • Gene Overview
    MyGene.info: DUSP12
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:170874187-170885878 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 77.27 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890614
protein coding gene Chr1:170873498-170885878 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016734
protein coding gene Chr1:176618614-176632762 (-)
A/J MGP_AJ_G0016714
protein coding gene Chr1:169422942-169435961 (-)
AKR/J MGP_AKRJ_G0016680
protein coding gene Chr1:174491709-174506330 (-)
BALB/cJ MGP_BALBcJ_G0016675
protein coding gene Chr1:169879794-169891957 (-)
C3H/HeJ MGP_C3HHeJ_G0016498
protein coding gene Chr1:174746334-174760639 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017136
protein coding gene Chr1:182455366-182481802 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014845
protein coding gene Chr1:161135320-161146886 (-)
CAST/EiJ MGP_CASTEiJ_G0016079
protein coding gene Chr1:174382949-174394488 (-)
CBA/J MGP_CBAJ_G0016473
protein coding gene Chr1:188952412-188966413 (-)
DBA/2J MGP_DBA2J_G0016580
protein coding gene Chr1:168261059-168273538 (-)
FVB/NJ MGP_FVBNJ_G0016577
protein coding gene Chr1:166630840-166644219 (-)
LP/J MGP_LPJ_G0016651
protein coding gene Chr1:177738724-177753243 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016603
protein coding gene Chr1:196268266-196282032 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017173
protein coding gene Chr1:174393186-174405702 (-)
PWK/PhJ MGP_PWKPhJ_G0015865
protein coding gene Chr1:167513285-167526367 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015649
protein coding gene Chr1:173142562-173170486 (-)
WSB/EiJ MGP_WSBEiJ_G0016141
protein coding gene Chr1:174513698-174525793 (-)



Homology
more
  • Human Ortholog
    DUSP12, dual specificity phosphatase 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DUSP12, dual specificity phosphatase 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DUSP1, YVH1
  • Links
    NCBI Gene ID: 11266
    neXtProt AC: NX_Q9UNI6
    UniProt: Q9UNI6

  • Chr Location
    1q23.3; chr1:161749692-161757164 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80915 NCBI Gene Model | MGI Sequence Detail 11692 C57BL/6J ±  kb
transcript NM_023173 RefSeq | MGI Sequence Detail 1413 Not Specified  
polypeptide NP_075662 RefSeq | MGI Sequence Detail 339 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 58
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1334415, MGI:1913471, MGI:2138549, MGI:3704201
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory