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Rnase2a
Gene Detail
 Symbol
Name
ID
Rnase2a
ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
MGI:1890465
Synonyms Ear11
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.44 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:51255266-51256112 bp, - strand
From Ensembl annotation of GRCm38

  847 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:121614  Vertebrate Homology Class
1 human; 2 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Rnase2a

Human
homologs
Human Homolog RNASE2, ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
NCBI Gene ID 6036
neXtProt AC  NX_P10153
Human Synonyms  EDN, RAF3, RNS2
Human Chr (Location)  14q11.2; chr14:20955471-20956435 (+)  GRCh38
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process RNA phosphodiester bond hydrolysis
Component extracellular vesicular exosome
Function endonuclease activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (11)    Tissues (1)    Images (11)
Theiler Stages: 23
Assay TypeResults
RNA in situ 11
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000047222 (Evidence)
Entrez Gene93726 (Evidence)
UniGene153688
DFCITC1589572
DoTSDT.484489
Consensus CDS ProjectCCDS27041.1
International Mouse Knockout Project StatusRnase2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047222 Ensembl Gene Model | MGI Sequence Detail 847 C57BL/6J ±  kb
transcript ENSMUST00000061936 Ensembl | MGI Sequence Detail 686 Not Applicable 
polypeptide ENSMUSP00000056418 Ensembl | MGI Sequence Detail 155 Not Applicable 

For the selected sequences
All sequences(13) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023411 Ribonuclease A, active site
InterPro IPR023412 Ribonuclease A-domain
References (Earliest) J:69087 Cormier SA, et al., Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis. Mamm Genome. 2001 May;12(5):352-61
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory