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Atp5e Gene Detail
Summary
  • Symbol
    Atp5e
  • Name
    ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
  • Synonyms
    2410043G19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1855697
    NCBI Gene: 67126
  • Gene Overview
    MyGene.info: ATP5F1E
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:174461075-174464101 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 97.95 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1855697
protein coding gene Chr2:174461072-174464105 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026969
protein coding gene Chr2:180821313-180824348 (-)
A/J MGP_AJ_G0026936
protein coding gene Chr2:173200163-173203198 (-)
AKR/J MGP_AKRJ_G0026907
protein coding gene Chr2:178415767-178418801 (-)
BALB/cJ MGP_BALBcJ_G0026945
protein coding gene Chr2:173597203-173600237 (-)
C3H/HeJ MGP_C3HHeJ_G0026687
protein coding gene Chr2:178795719-178798752 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027392
protein coding gene Chr2:186013105-186016138 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024761
protein coding gene Chr2:166435190-166438225 (-)
CAST/EiJ MGP_CASTEiJ_G0026146
protein coding gene Chr2:179524639-179527677 (-)
CBA/J MGP_CBAJ_G0026664
protein coding gene Chr2:192946608-192949642 (-)
DBA/2J MGP_DBA2J_G0026802
protein coding gene Chr2:172298920-172301953 (-)
FVB/NJ MGP_FVBNJ_G0026768
protein coding gene Chr2:170922702-170925720 (-)
LP/J MGP_LPJ_G0026903
protein coding gene Chr2:180733223-180736258 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026787
protein coding gene Chr2:195838034-195841058 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027449
protein coding gene Chr2:178444833-178447866 (-)
PWK/PhJ MGP_PWKPhJ_G0025882
protein coding gene Chr2:172113663-172116692 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025682
protein coding gene Chr2:177491464-177495884 (-)
WSB/EiJ MGP_WSBEiJ_G0026218
protein coding gene Chr2:179408920-179411953 (-)



Homology
more
  • Human Ortholog
    ATP5F1E, ATP synthase F1 subunit epsilon
  • Human Ortholog
    ATP5F1E, ATP synthase F1 subunit epsilon
    Orthology source: HGNC
  • Synonyms
    ATP5E, ATPE, MC5DN3
  • Links
    NCBI Gene ID: 514
    neXtProt AC: NX_P56381
    UniProt: P56381

  • Chr Location
    20q13.32; chr20:59028678-59032367 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ATP5F1E associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67126 NCBI Gene Model | MGI Sequence Detail 3027 C57BL/6J ±  kb
    transcript NM_025983 RefSeq | MGI Sequence Detail 419 C57BL/6  
    polypeptide P56382 UniProt | EBI | MGI Sequence Detail 52 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000004457 ATP synthase subunit epsilon, mitochondrial
    • InterPro Domains
      IPR006721 ATP synthase, F1 complex, epsilon subunit, mitochondrial
      IPR036742 ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial
    Molecular
    Reagents
    less
    • All nucleic 143
      cDNA 143

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1914376, MGI:2139226
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:61560 Tu Q, et al., Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif. Biochem J. 2000 Apr 1;347 Pt 1:17-21
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    06/11/2019
    MGI 6.14
    The Jackson Laboratory