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Copb2
Gene Detail
Symbol

Name
ID
Copb2
coatomer protein complex, subunit beta 2 (beta prime)
MGI:1354962
Feature Type
protein coding gene
Genetic Map
Chromosome 9
51.40 cM, cytoband E3-F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:98563721-98588382 bp, + strand
From VEGA annotation of GRCm38

  24662 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3499  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: coatomer, beta' subunit
Gene Tree: Copb2

Human
homologs
Human Homolog COPB2, coatomer protein complex, subunit beta 2 (beta prime)
NCBI Gene ID 9276
neXtProt AC  NX_P35606
Human Synonyms  beta'-COP
Human Chr (Location)  3q23; chr3:139357591-139389680 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from APF )
Interactions
Copb2 interacts with 74 markers (Mir1b, Mir30a, Mir30d, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process intracellular protein transport, intra-Golgi vesicle-mediated transport, ...
Component COPI vesicle coat, cytoplasm, ...
Function protein kinase C binding, structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (150)    Tissues (25)    Images (29)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 150
cDNA source data(271)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(272) cDNA(272)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000047583 (Evidence)
Ensembl Gene ModelENSMUSG00000032458 (Evidence)
Entrez Gene50797 (Evidence)
UniGene400464
DFCITC1679879, TC1627467, TC1573946
DoTSDT.94199271, DT.494210, DT.91588236
NIA Mouse Gene IndexU010896
Consensus CDS ProjectCCDS40734.1
International Mouse Knockout Project StatusCopb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047583 VEGA Gene Model | MGI Sequence Detail 24662 C57BL/6J ±  kb
transcript OTTMUST00000122715 VEGA | MGI Sequence Detail 3050 Not Applicable 
polypeptide OTTMUSP00000067228 VEGA | MGI Sequence Detail 905 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(227 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016453 Coatomer beta' subunit (COPB2)
InterPro IPR006692 Coatomer, WD associated region
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000005735 coatomer subunit beta'
References
(Earliest) J:42235 Hosaka M, et al., Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6). J Biochem. 1996 Oct;120(4):813-9
(Latest) J:210665 Shi F, et al., A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet. 2014 Jul 15;23(14):3792-800
All references(39)
Other
accession IDs
MGI:2143003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory