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Csnk1e
Gene Detail
 Symbol
Name
ID
Csnk1e
casein kinase 1, epsilon
MGI:1351660
Synonyms CK1epsilon, CKIepsilon, CKI epsilon, KC1epsilon, tau
Feature Type protein coding gene
Genetic Map
Chromosome 15
37.71 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr15:79417856-79443919 bp, - strand
From VEGA annotation of GRCm38

  26064 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:121695  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Csnk1e

Human
homologs
Human Homolog CSNK1E, casein kinase 1, epsilon
NCBI Gene ID 1454
neXtProt AC  NX_P49674
Human Synonyms  CKIepsilon, HCKIE
Human Chr (Location)  22q13.1; chr22:38290691-38318084 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(63) : Gene trapped(55) Radiation induced(1) Targeted(7)
Genomic Mutations involving Csnk1e (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit disruptions in circadian rhythms.
 
Interactions
Csnk1e interacts with 200 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process cellular protein localization, circadian regulation of gene expression, ...
Component cytoplasm, nucleus, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (281)    Tissues (177)    Images (42)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 277
Western blot 4
cDNA source data(134)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(136) cDNA(135) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000029589 (Evidence)
Ensembl Gene ModelENSMUSG00000022433 (Evidence)
Entrez Gene27373 (Evidence)
UniGene30199
DFCITC1575357, TC1615175, TC1685811
DoTSDT.55100184, DT.55220996, DT.91391696
NIA Mouse Gene IndexU036405
EC2.7.11.1
Consensus CDS ProjectCCDS27640.1, CCDS70646.1
International Mouse Knockout Project StatusCsnk1e
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029589 VEGA Gene Model | MGI Sequence Detail 26064 C57BL/6J ±  kb
transcript OTTMUST00000073380 VEGA | MGI Sequence Detail 2694 Not Applicable 
polypeptide OTTMUSP00000037966 VEGA | MGI Sequence Detail 416 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(24) UniProt(6)
Polymorphisms PCR(1) : SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000005946 casein kinase I isoform epsilon
References (Earliest) J:59123 Kusuda J, et al., cDNA cloning and chromosome mapping of the mouse casein kinase I epsilon gene (Csnk1e). Cytogenet Cell Genet. 1999;87(1-2):99-101
(Latest) J:210023 Duong HA, et al., Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes. Nat Struct Mol Biol. 2014 Feb;21(2):126-32
All references(68)
Other
accession IDs
MGI:2145998, MGI:2146039, MGI:2146216

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory