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Ndufb11 Gene Detail
Summary
  • Symbol
    Ndufb11
  • Name
    NADH:ubiquinone oxidoreductase subunit B11
  • Synonyms
    D5Bwg0566e, D5Bwg0577e, Np15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349919
    NCBI Gene: 104130
  • Gene Overview
    MyGene.info: NDUFB11
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:20615326-20617564 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 16.11 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349919
 protein coding gene ChrX:20615326-20617619 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035592
 protein coding gene ChrX:15500215-15502512 (-)
A/J MGP_AJ_G0035569
 protein coding gene ChrX:15590805-15593989 (-)
AKR/J MGP_AKRJ_G0035502
 protein coding gene ChrX:16124320-16126613 (-)
BALB/cJ MGP_BALBcJ_G0035562
 protein coding gene ChrX:15339723-15342016 (-)
C3H/HeJ MGP_C3HHeJ_G0035280
 protein coding gene ChrX:15719331-15721626 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036098
 protein coding gene ChrX:15899583-15908757 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032962
 protein coding gene ChrX:13847595-13849946 (-)
CAST/EiJ MGP_CASTEiJ_G0034571
 protein coding gene ChrX:15013872-15016169 (-)
CBA/J MGP_CBAJ_G0035249
 protein coding gene ChrX:16646316-16648609 (-)
DBA/2J MGP_DBA2J_G0035401
 protein coding gene ChrX:15395439-15397848 (-)
FVB/NJ MGP_FVBNJ_G0035347
 protein coding gene ChrX:15295577-15297871 (-)
LP/J MGP_LPJ_G0035483
 protein coding gene ChrX:15750528-15752821 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035391
 protein coding gene ChrX:16901221-16903514 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036105
 protein coding gene ChrX:15410983-15413280 (-)
PWK/PhJ MGP_PWKPhJ_G0034272
 protein coding gene ChrX:14582628-14585130 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034112
 protein coding gene ChrX:15392458-15395670 (-)
WSB/EiJ MGP_WSBEiJ_G0034706
 protein coding gene ChrX:15282214-15284507 (-)



Homology
more
  • Human Ortholog
    NDUFB11, NADH:ubiquinone oxidoreductase subunit B11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NDUFB11, NADH:ubiquinone oxidoreductase subunit B11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CI-ESSS, ESSS, Np15, NP17.3, P17.3
  • Links
    NCBI Gene ID: 54539
    neXtProt AC: NX_Q9NX14
    UniProt: Q9NX14

  • Chr Location
    Xp11.3; chrX:47142216-47145210 (-)  GRCh38.p7
Human Diseases
more
  • Diseases
    2 with human NDUFB11 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    115
  • Tissues
    89
  • cDNA Data
    176
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 104130 NCBI Gene Model | MGI Sequence Detail 2239 C57BL/6J ±  kb
transcript NM_019435 RefSeq | MGI Sequence Detail 908 C57BL/6  
polypeptide O09111 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000011085 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
    (term hierarchy)
  • PDB
    6G2J, 6G72
  • InterPro Domains
    IPR019329 NADH:ubiquinone oxidoreductase, ESSS subunit
Molecular
Reagents
less
  • All nucleic 180
    cDNA 176
    Primer pair 4

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34182, MGD-MRK-34183, MGI:106488, MGI:106489, MGI:2136540
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:257477 Kim C, et al., An X-chromosome linked mouse model (Ndufa1(S55A)) for systemic partial Complex I deficiency for studying predisposition to neurodegeneration and other diseases. Neurochem Int. 2017 Oct;109:78-93
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/13/2018
MGI 6.13 		The Jackson Laboratory